Sodium lauryl sulfoacetate

Name: Sodium lauryl sulfoacetate
Brand: MedChemExpress
SKU: HY-107789
Rating: 4.5 (1 reviews)

Cat. No.: HY-107789 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Sodium lauryl sulfoacetate is a solid anionic surfactant of plant origin. Sodium lauryl sulfoacetate is an immunoadjuvant with antiimmunosuppressive effects. Sodium lauryl sulfoacetate has antiviral activity.

For research use only. We do not sell to patients.

Sodium lauryl sulfoacetate Chemical Structure

CAS No. : 1847-58-1

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25 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 90	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
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500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Sodium lauryl sulfoacetate (62.5, 125, 250, or 500 mug/mL, 44 h) can promote the proliferation of lymphocytes in chicken peripheral blood monocytes^[1].
Sodium lauryl sulfoacetate (10, 20, 30, 40, 50 μM, 1 h) decreases the infectivity of herpes virus to Vero cells in a concentration-dependent manner^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[3]

Cell Line:	HSV-1, HSV-2
Concentration:	12.5, 25, 37.5 μM
Incubation Time:	24 h
Result:	Decreased the infectivities for Vero cells in a concentration-dependent manner.

In Vivo

Sodium lauryl sulfoacetate (1.0, 2.0, or 4.0 mg/kg intramuscular injection for 3 consecutive days) can promote the NDV-specific antibody response of thiomycin-treated chickens^[1].
Sodium lauryl sulfoacetate (5% SLC gel) significantly decreases the mean lesion score of herpes simplex virus type 1 (HSV-1)^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

330.42

Formula

C₁₄H₂₇NaO₅S

CAS No.

1847-58-1

Appearance

Solid

Color

White to off-white

SMILES

O=C(OCCCCCCCCCCCC)CS(=O)(O[Na])=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 15.62 mg/mL (47.27 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0265 mL	15.1323 mL	30.2645 mL
5 mM	0.6053 mL	3.0265 mL	6.0529 mL
10 mM	0.3026 mL	1.5132 mL	3.0265 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: 2.08 mg/mL (6.30 mM); Suspended solution; Need ultrasonic

This protocol yields a suspended solution of 2.08 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (6.30 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.08 mg/mL (6.30 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (240 KB) HNMR (258 KB)

Handling Instructions (2659 KB)

References

[1]. Cheng D, et al. The immune enhancement of sodium lauryl sulfoacetate in chickens. Vet Med Int. 2010;2010:485060. [Content Brief]

[2]. Piret J,et al. Sodium lauryl sulfate, a microbicide effective against enveloped and nonenveloped viruses. Curr Drug Targets. 2002 Feb;3(1):17-30. [Content Brief]

[3]. Piret J, et al. Sodium lauryl sulfate increases the efficacy of a topical formulation of foscarnet against herpes simplex virus type 1 cutaneous lesions in mice. Antimicrob Agents Chemother. 2000 Sep;44(9):2263-70. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0265 mL	15.1323 mL	30.2645 mL	75.6613 mL
	5 mM	0.6053 mL	3.0265 mL	6.0529 mL	15.1323 mL
	10 mM	0.3026 mL	1.5132 mL	3.0265 mL	7.5661 mL
	15 mM	0.2018 mL	1.0088 mL	2.0176 mL	5.0441 mL
	20 mM	0.1513 mL	0.7566 mL	1.5132 mL	3.7831 mL
	25 mM	0.1211 mL	0.6053 mL	1.2106 mL	3.0265 mL
	30 mM	0.1009 mL	0.5044 mL	1.0088 mL	2.5220 mL
	40 mM	0.0757 mL	0.3783 mL	0.7566 mL	1.8915 mL