Mazisotine

Cat. No.: HY-139347 Purity: 99.09%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

SSTR4 agonist-1 (Compound 47) is a selective agonist for somatostatin receptor subtype 4 (SSTR4) with an EC₅₀ of 4.7 nM. SSTR4 agonist-1 reveals a half-life > 130 minutes in human liver microsomes.

For research use only. We do not sell to patients.

Mazisotine Chemical Structure

CAS No. : 1638588-92-7

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of Mazisotine:

Mazisotine tartrate Get quote

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View All Somatostatin Receptor Isoform Specific Products:

View All Isoforms

SSTR1 SSTR2 SSTR3 SSTR5 SSTR4

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

SSTR4

4.7 nM (EC₅₀)

Molecular Weight

289.37

Formula

C₁₆H₂₃N₃O₂

CAS No.

1638588-92-7

Appearance

Solid

Color

White to off-white

SMILES

CC(C=CC=N1)=C1OCC(C)(C)NC([C@H]2[C@@]3([H])[C@]2([H])CNC3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (431.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4558 mL	17.2789 mL	34.5578 mL
5 mM	0.6912 mL	3.4558 mL	6.9116 mL
10 mM	0.3456 mL	1.7279 mL	3.4558 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.09%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (248 KB) HNMR (262 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Giovannini R, et al., New somatostatin receptor subtype 4 (sstr4) agonists. WO2014184275 A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.4558 mL	17.2789 mL	34.5578 mL	86.3946 mL
	5 mM	0.6912 mL	3.4558 mL	6.9116 mL	17.2789 mL
	10 mM	0.3456 mL	1.7279 mL	3.4558 mL	8.6395 mL
	15 mM	0.2304 mL	1.1519 mL	2.3039 mL	5.7596 mL
	20 mM	0.1728 mL	0.8639 mL	1.7279 mL	4.3197 mL
	25 mM	0.1382 mL	0.6912 mL	1.3823 mL	3.4558 mL
	30 mM	0.1152 mL	0.5760 mL	1.1519 mL	2.8798 mL
	40 mM	0.0864 mL	0.4320 mL	0.8639 mL	2.1599 mL
	50 mM	0.0691 mL	0.3456 mL	0.6912 mL	1.7279 mL
	60 mM	0.0576 mL	0.2880 mL	0.5760 mL	1.4399 mL
	80 mM	0.0432 mL	0.2160 mL	0.4320 mL	1.0799 mL
	100 mM	0.0346 mL	0.1728 mL	0.3456 mL	0.8639 mL

Mazisotine Related Classifications

Neurological Disease Inflammation/Immunology

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mazisotine1638588-92-7Somatostatin ReceptorSSTRsSSTRselectiveInhibitorinhibitorinhibit

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