2. Membrane Transporter/Ion Channel Epigenetics
  3. Potassium Channel TET Protein
  4. Succinic acid sodium

Succinic acid sodium  (Synonyms: Wormwood acid sodium)

Cat. No.: HY-W396714
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Succinic acid sodium is a potent and orally active anxiolytic agent. Succinic acid sodium shows inhibitory effects on colonic epithelial cell proliferation in vivo. Succinic acid sodium can down-regulate the expression of KCNMB1 (potassium channel subunit β1) and TET1 (ten?eleven translocation 1). Succinic acid sodium can be used for gestational hypertension research.

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Succinic acid sodium Chemical Structure

Succinic acid sodium Chemical Structure

CAS No. : 14047-56-4

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Succinic acid sodium Related Antibodies

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Description

Succinic acid sodium is a potent and orally active anxiolytic agent. Succinic acid sodium shows inhibitory effects on colonic epithelial cell proliferation in vivo. Succinic acid sodium can down-regulate the expression of KCNMB1 (potassium channel subunit β1) and TET1 (ten?eleven translocation 1). Succinic acid sodium can be used for gestational hypertension research[1][2][3].

IC50 & Target[1][2][3]

TET1

 

In Vivo

Succinic acid sodium (3.0 or 6.0 mg/kg, PO) increased the percentage of entries into open arms and of time spent on open arms[1].
succinic acid (3.0, 6.0, and 12.0 mg/kg, IP) caused significant increases in food intake during 5 min when compared with the vehicle[1].
Succinic acid sodium (100 mM) infused into rat colons significantly inhibits colonic cell proliferation and reduced crypt size[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Formula

C4H6O4.xNa
CAS No.
SMILES

O=C(CCC(O)=O)O.[Na].[x]
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Succinic acid sodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Succinic acid14047-56-4Wormwood acidPotassium ChannelTET ProteinKcsATET enzymeTen-eleven-translocation (TET) proteinTen-eleven translocation (TET) methylcytosine dioxygenaseanxiolyticshort-chain fatty acidslarge intestinecell divisiongestational hypertensionInhibitorinhibitorinhibit

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