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  4. Sulfobetaine-12

Sulfobetaine-12is a zwitterionic surfactant, which means it has both positive and negative charges in its molecules. It is used as a detergent in various industries, including pharmaceuticals, cosmetics, and personal care products. Sulfobetaine-12Often used as a mild surfactant due to its non-irritating properties and ability to stabilize emulsions. Plus, it has antistatic properties that can be used to clean electronics and other static-prone surfaces.

For research use only. We do not sell to patients.

Sulfobetaine-12 Chemical Structure

Sulfobetaine-12 Chemical Structure

CAS No. : 14933-08-5

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1 g USD 30 In-stock
5 g USD 55 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Sulfobetaine-12 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

Sulfobetaine-12is a zwitterionic surfactant, which means it has both positive and negative charges in its molecules. It is used as a detergent in various industries, including pharmaceuticals, cosmetics, and personal care products. Sulfobetaine-12Often used as a mild surfactant due to its non-irritating properties and ability to stabilize emulsions. Plus, it has antistatic properties that can be used to clean electronics and other static-prone surfaces.

In Vitro

Sulfobetaine-12 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sulfobetaine-12 Related Antibodies
Molecular Weight

335.55

Formula

C17H37NO3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCC[N+](C)(C)CCCS(=O)(=O)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (149.01 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9802 mL 14.9009 mL 29.8018 mL
5 mM 0.5960 mL 2.9802 mL 5.9604 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (7.45 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (7.45 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9802 mL 14.9009 mL 29.8018 mL 74.5045 mL
5 mM 0.5960 mL 2.9802 mL 5.9604 mL 14.9009 mL
10 mM 0.2980 mL 1.4901 mL 2.9802 mL 7.4505 mL
15 mM 0.1987 mL 0.9934 mL 1.9868 mL 4.9670 mL
20 mM 0.1490 mL 0.7450 mL 1.4901 mL 3.7252 mL
25 mM 0.1192 mL 0.5960 mL 1.1921 mL 2.9802 mL
30 mM 0.0993 mL 0.4967 mL 0.9934 mL 2.4835 mL
40 mM 0.0745 mL 0.3725 mL 0.7450 mL 1.8626 mL
50 mM 0.0596 mL 0.2980 mL 0.5960 mL 1.4901 mL
60 mM 0.0497 mL 0.2483 mL 0.4967 mL 1.2417 mL
80 mM 0.0373 mL 0.1863 mL 0.3725 mL 0.9313 mL
100 mM 0.0298 mL 0.1490 mL 0.2980 mL 0.7450 mL
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Sulfobetaine-12 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfobetaine-1214933-08-5Sulfobetaine12Sulfobetaine 12Biochemical Assay Reagentsbiochemical assayreagentInhibitorinhibitorinhibit

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