2. Anti-infection
  3. HIV
  4. Tenofovir diphosphate disodium

Tenofovir diphosphate disodium  (Synonyms: TFV-DP disodium)

Cat. No.: HY-136548B Purity: 98.36%
SDS COA Handling Instructions

Molarity Calculator

Tenofovir diphosphate disodium is an antiretroviral agent and an inhibitor of DNA polymerases. Tenofovir diphosphate disodium is a substrate of HIV-1 reverse transcriptase (RT). Tenofovir diphosphate disodium can be used for the research of Aids.

For research use only. We do not sell to patients.

Tenofovir diphosphate disodium Chemical Structure

Tenofovir diphosphate disodium Chemical Structure

CAS No. : 2738719-07-6

Size Price Stock Quantity
1 mg USD 380 In-stock
5 mg USD 680 In-stock
10 mg USD 1080 In-stock
25 mg USD 2150 In-stock
50 mg USD 3450 In-stock
100 mg USD 5500 In-stock
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500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Tenofovir diphosphate disodium Related Antibodies

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1 Publications Citing Use of MCE Tenofovir diphosphate disodium

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Description

Tenofovir diphosphate disodium is an antiretroviral agent and an inhibitor of DNA polymerases. Tenofovir diphosphate disodium is a substrate of HIV-1 reverse transcriptase (RT). Tenofovir diphosphate disodium can be used for the research of Aids[1].

Molecular Weight

491.14

Formula

C9H14N5Na2O10P3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@H](OC[P](O[P](O[P](O[Na])(O[Na])=O)(O)=O)(O)=O)CN1C2=NC=NC(N)=C2N=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (203.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0361 mL 10.1804 mL 20.3608 mL
5 mM 0.4072 mL 2.0361 mL 4.0722 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.36%

SDS (252 KB)

COA (248 KB) HNMR (216 KB) CNMR (242 KB) LCMS (111 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.0361 mL 10.1804 mL 20.3608 mL 50.9020 mL
5 mM 0.4072 mL 2.0361 mL 4.0722 mL 10.1804 mL
10 mM 0.2036 mL 1.0180 mL 2.0361 mL 5.0902 mL
15 mM 0.1357 mL 0.6787 mL 1.3574 mL 3.3935 mL
20 mM 0.1018 mL 0.5090 mL 1.0180 mL 2.5451 mL
25 mM 0.0814 mL 0.4072 mL 0.8144 mL 2.0361 mL
30 mM 0.0679 mL 0.3393 mL 0.6787 mL 1.6967 mL
40 mM 0.0509 mL 0.2545 mL 0.5090 mL 1.2725 mL
50 mM 0.0407 mL 0.2036 mL 0.4072 mL 1.0180 mL
60 mM 0.0339 mL 0.1697 mL 0.3393 mL 0.8484 mL
80 mM 0.0255 mL 0.1273 mL 0.2545 mL 0.6363 mL
100 mM 0.0204 mL 0.1018 mL 0.2036 mL 0.5090 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Tenofovir diphosphate disodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tenofovir diphosphate disodium2738719-07-6TFV-DP disodiumHIVHuman immunodeficiency virusDNApolymerasessubstrateHIV-1reversetranscriptaseInhibitorinhibitorinhibit

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