2. Metabolic Enzyme/Protease
  3. Acetolactate Synthase (ALS)
  4. Terbuthylazine-d5

Terbuthylazine-d5 is the deuterium labeled Terbuthylazine[1]. Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide[2].

For research use only. We do not sell to patients.

Terbuthylazine-d<sub>5</sub> Chemical Structure

Terbuthylazine-d5 Chemical Structure

CAS No. : 222986-60-9

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Based on 1 publication(s) in Google Scholar

Other Forms of Terbuthylazine-d5:

Terbuthylazine-d5 Related Antibodies

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Description

Terbuthylazine-d5 is the deuterium labeled Terbuthylazine[1]. Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Terbuthylazine-d5 Related Antibodies
Molecular Weight

234.74

Formula

C9H11D5ClN5
CAS No.
Unlabeled CAS

5915-41-3
Appearance

Solid

Color

White to off-white

SMILES

CC(C)(C)NC1=NC(Cl)=NC(NC([2H])([2H])C([2H])([2H])[2H])=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (127.80 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 30 mg/mL (127.80 mM)

DMSO : ≥ 30 mg/mL (127.80 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 30 mg/mL (127.80 mM)

Ethanol : ≥ 1 mg/mL (4.26 mM)

Ethanol : ≥ 1 mg/mL (4.26 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2600 mL 21.3002 mL 42.6003 mL
5 mM 0.8520 mL 4.2600 mL 8.5201 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / Ethanol / DMSO / DMF / DMSO / DMF 1 mM 4.2600 mL 21.3002 mL 42.6003 mL 106.5008 mL
DMSO / DMF / DMSO / DMF 5 mM 0.8520 mL 4.2600 mL 8.5201 mL 21.3002 mL
10 mM 0.4260 mL 2.1300 mL 4.2600 mL 10.6501 mL
15 mM 0.2840 mL 1.4200 mL 2.8400 mL 7.1001 mL
20 mM 0.2130 mL 1.0650 mL 2.1300 mL 5.3250 mL
25 mM 0.1704 mL 0.8520 mL 1.7040 mL 4.2600 mL
30 mM 0.1420 mL 0.7100 mL 1.4200 mL 3.5500 mL
40 mM 0.1065 mL 0.5325 mL 1.0650 mL 2.6625 mL
50 mM 0.0852 mL 0.4260 mL 0.8520 mL 2.1300 mL
60 mM 0.0710 mL 0.3550 mL 0.7100 mL 1.7750 mL
80 mM 0.0533 mL 0.2663 mL 0.5325 mL 1.3313 mL
100 mM 0.0426 mL 0.2130 mL 0.4260 mL 1.0650 mL
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Terbuthylazine-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Terbuthylazine-d5222986-60-9Acetolactate Synthase (ALS)Acetohydroxyacid synthaseInhibitorinhibitorinhibit

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