Terephthalaldehyde (Synonyms: Terephthalaldehyde)

Cat. No.: HY-Y0425 Purity: 98.79%: FAQs
Data Sheet SDS COA Handling Instructions

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Terephthalaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

Terephthalaldehyde Chemical Structure

CAS No. : 623-27-8

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10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
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10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
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500 mg	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Terephthalaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research^[1].

Molecular Weight

134.13

Formula

C₈H₆O₂

CAS No.

623-27-8

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=CC1=CC=C(C=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

Ethanol : 40 mg/mL (298.22 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.4555 mL	37.2773 mL	74.5545 mL
5 mM	1.4911 mL	7.4555 mL	14.9109 mL
10 mM	0.7455 mL	3.7277 mL	7.4555 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% EtOH 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 4 mg/mL (29.82 mM); Clear solution

This protocol yields a clear solution of ≥ 4 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (40.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% EtOH 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 4 mg/mL (29.82 mM); Clear solution

This protocol yields a clear solution of ≥ 4 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (40.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% EtOH 90% Corn Oil
Solubility: ≥ 4 mg/mL (29.82 mM); Clear solution

This protocol yields a clear solution of ≥ 4 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (40.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.92%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (246 KB) HNMR (114 KB) GC (194 KB)

Handling Instructions (2659 KB)

References

[1]. Garg M, et al. Terephthalaldehyde as a good crosslinking agent in crosslinked chitosan hydrogel for the selective removal of anionic dyes[J]. New Journal of Chemistry, 2021, 45(11): 4938-4949.

[2]. Gomha S M, Farghaly T A, Abbas E M H, et al. Terephthalaldehyde: An Effecient Key Precursor for Novel Synthesis of Some Interesting Bis‐thiazoles and Bis‐triazolopyrimidinones[J]. Journal of Heterocyclic Chemistry, 2018, 55(3): 750-755.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol	1 mM	7.4555 mL	37.2773 mL	74.5545 mL	186.3863 mL
	5 mM	1.4911 mL	7.4555 mL	14.9109 mL	37.2773 mL
	10 mM	0.7455 mL	3.7277 mL	7.4555 mL	18.6386 mL
	15 mM	0.4970 mL	2.4852 mL	4.9703 mL	12.4258 mL
	20 mM	0.3728 mL	1.8639 mL	3.7277 mL	9.3193 mL
	25 mM	0.2982 mL	1.4911 mL	2.9822 mL	7.4555 mL
	30 mM	0.2485 mL	1.2426 mL	2.4852 mL	6.2129 mL
	40 mM	0.1864 mL	0.9319 mL	1.8639 mL	4.6597 mL
	50 mM	0.1491 mL	0.7455 mL	1.4911 mL	3.7277 mL
	60 mM	0.1243 mL	0.6213 mL	1.2426 mL	3.1064 mL
	80 mM	0.0932 mL	0.4660 mL	0.9319 mL	2.3298 mL
	100 mM	0.0746 mL	0.3728 mL	0.7455 mL	1.8639 mL

Terephthalaldehyde Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Terephthalaldehyde623-27-8Biochemical Assay Reagentsdrug synthesisbis-thiazolesbis-triazolopyrimidinonesCAATCAAGInhibitorinhibitorinhibit

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Terephthalaldehyde (Synonyms: Terephthalaldehyde)

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Terephthalaldehyde Related Antibodies

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Complete Stock Solution Preparation Table

Terephthalaldehyde Related Classifications

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