2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Tetrahydro-11-deoxycortisol

Tetrahydro-11-deoxycortisol  (Synonyms: Tetrahydrodeoxycortisol)

Cat. No.: HY-113423 Purity: 98.2%
SDS COA Handling Instructions Technical Support

Tetrahydro-11-deoxycortisol (Tetrahydrodeoxycortisol) is an endogenous metabolite present in Urine that can be used for the research of 11 Beta Hydroxylase Deficiency.

For research use only. We do not sell to patients.

Tetrahydro-11-deoxycortisol Chemical Structure

Tetrahydro-11-deoxycortisol Chemical Structure

CAS No. : 68-60-0

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Based on 1 publication(s) in Google Scholar

Tetrahydro-11-deoxycortisol Related Antibodies

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Description

Tetrahydro-11-deoxycortisol (Tetrahydrodeoxycortisol) is an endogenous metabolite present in Urine that can be used for the research of 11 Beta Hydroxylase Deficiency[1][2].

In Vitro

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tetrahydro-11-deoxycortisol Related Antibodies
Molecular Weight

350.49

Formula

C21H34O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]1(CC2)[C@](CC[C@@]1(C(CO)=O)O)([H])[C@@]3([H])[C@@]2([H])[C@](CC[C@@H](O)C4)(C)[C@]4([H])CC3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 30 mg/mL (85.59 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8531 mL 14.2657 mL 28.5315 mL
5 mM 0.5706 mL 2.8531 mL 5.7063 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.2%

SDS (251 KB)

COA (254 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8531 mL 14.2657 mL 28.5315 mL 71.3287 mL
5 mM 0.5706 mL 2.8531 mL 5.7063 mL 14.2657 mL
10 mM 0.2853 mL 1.4266 mL 2.8531 mL 7.1329 mL
15 mM 0.1902 mL 0.9510 mL 1.9021 mL 4.7552 mL
20 mM 0.1427 mL 0.7133 mL 1.4266 mL 3.5664 mL
25 mM 0.1141 mL 0.5706 mL 1.1413 mL 2.8531 mL
30 mM 0.0951 mL 0.4755 mL 0.9510 mL 2.3776 mL
40 mM 0.0713 mL 0.3566 mL 0.7133 mL 1.7832 mL
50 mM 0.0571 mL 0.2853 mL 0.5706 mL 1.4266 mL
60 mM 0.0476 mL 0.2378 mL 0.4755 mL 1.1888 mL
80 mM 0.0357 mL 0.1783 mL 0.3566 mL 0.8916 mL
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Tetrahydro-11-deoxycortisol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetrahydro-11-deoxycortisol68-60-0TetrahydrodeoxycortisolEndogenous MetaboliteInhibitorinhibitorinhibit

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