2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease Anti-infection
  3. DNA/RNA Synthesis Endogenous Metabolite Orthopoxvirus
  4. Thymidine-13C10,15N2

Thymidine-13C10,15N2  (Synonyms: DThyd-13C10,15N2; NSC-13C10,15N2)

Cat. No.: HY-N1150S8 Purity: 99.90%
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Thymidine-13C10,15N2 is the 13C and 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].

For research use only. We do not sell to patients.

Thymidine-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>2</sub> Chemical Structure

Thymidine-13C10,15N2 Chemical Structure

CAS No. : 1821188-00-4

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1 mg USD 215 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Thymidine-13C10,15N2:

Thymidine-13C10,15N2 Related Antibodies

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Description

Thymidine-13C10,15N2 is the 13C and 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Thymidine-13C10,15N2 Related Antibodies
Molecular Weight

254.14

Formula

13C10H1415N2O5
CAS No.
Unlabeled CAS

50-89-5
Appearance

Solid

Color

White to off-white

SMILES

O=[13C]([15N]([13C@H](O[13C@@H]1[13CH2]O)[13CH2][13C@@H]1O)[13CH]=[13C]2[13CH3])[15NH][13C]2=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (196.74 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9348 mL 19.6742 mL 39.3484 mL
5 mM 0.7870 mL 3.9348 mL 7.8697 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9348 mL 19.6742 mL 39.3484 mL 98.3710 mL
5 mM 0.7870 mL 3.9348 mL 7.8697 mL 19.6742 mL
10 mM 0.3935 mL 1.9674 mL 3.9348 mL 9.8371 mL
15 mM 0.2623 mL 1.3116 mL 2.6232 mL 6.5581 mL
20 mM 0.1967 mL 0.9837 mL 1.9674 mL 4.9185 mL
25 mM 0.1574 mL 0.7870 mL 1.5739 mL 3.9348 mL
30 mM 0.1312 mL 0.6558 mL 1.3116 mL 3.2790 mL
40 mM 0.0984 mL 0.4919 mL 0.9837 mL 2.4593 mL
50 mM 0.0787 mL 0.3935 mL 0.7870 mL 1.9674 mL
60 mM 0.0656 mL 0.3279 mL 0.6558 mL 1.6395 mL
80 mM 0.0492 mL 0.2459 mL 0.4919 mL 1.2296 mL
100 mM 0.0393 mL 0.1967 mL 0.3935 mL 0.9837 mL
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Thymidine-13C10,15N2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thymidine-13C10,15N21821188-00-4DThyd-13C10,15N2NSC-13C10,15N2DNA/RNA SynthesisEndogenous MetaboliteOrthopoxvirusInhibitorinhibitorinhibit

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