2. Metabolic Enzyme/Protease Anti-infection
  3. Endogenous Metabolite Parasite
  4. Toltrazuril sulfoxide

Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.

For research use only. We do not sell to patients.

Toltrazuril sulfoxide Chemical Structure

Toltrazuril sulfoxide Chemical Structure

CAS No. : 69004-15-5

Size Price Stock Quantity
1 mg USD 150 In-stock
5 mg USD 460 In-stock
10 mg USD 760 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Toltrazuril sulfoxide:

Toltrazuril sulfoxide Related Antibodies

Top Publications Citing Use of Products

View All Parasite Isoform Specific Products:

View All Isoforms
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites[1].

IC50 & Target

Coccidia

 

Molecular Weight

441.38

Formula

C18H14F3N3O5S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N(C1=CC=C(OC2=CC=C(S(C(F)(F)F)=O)C=C2)C(C)=C1)C(N3)=O)N(C)C3=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (566.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2656 mL 11.3281 mL 22.6562 mL
5 mM 0.4531 mL 2.2656 mL 4.5312 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.55%

COA (248 KB) HNMR (263 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2656 mL 11.3281 mL 22.6562 mL 56.6405 mL
5 mM 0.4531 mL 2.2656 mL 4.5312 mL 11.3281 mL
10 mM 0.2266 mL 1.1328 mL 2.2656 mL 5.6641 mL
15 mM 0.1510 mL 0.7552 mL 1.5104 mL 3.7760 mL
20 mM 0.1133 mL 0.5664 mL 1.1328 mL 2.8320 mL
25 mM 0.0906 mL 0.4531 mL 0.9062 mL 2.2656 mL
30 mM 0.0755 mL 0.3776 mL 0.7552 mL 1.8880 mL
40 mM 0.0566 mL 0.2832 mL 0.5664 mL 1.4160 mL
50 mM 0.0453 mL 0.2266 mL 0.4531 mL 1.1328 mL
60 mM 0.0378 mL 0.1888 mL 0.3776 mL 0.9440 mL
80 mM 0.0283 mL 0.1416 mL 0.2832 mL 0.7080 mL
100 mM 0.0227 mL 0.1133 mL 0.2266 mL 0.5664 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Toltrazuril sulfoxide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Toltrazuril sulfoxide69004-15-5Endogenous MetaboliteParasiteTZR-SOintermediarymetaboliteantiprotozoalInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Toltrazuril sulfoxide
Cat. No.:
HY-136438
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.