trans-R-138727

Cat. No.: HY-123669A: FAQs
Data Sheet Handling Instructions

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Trans-R-138727 is the trans isomer of R-138727 (HY-123669). R-138727 is the active metabolite of the antiplatelet agent Prasugrel (HY-15284). R-138727 is an irreversible inhibitor for the platelet receptor P2Y12, and inhibits ADP-induced platelet activation and aggregation.

For research use only. We do not sell to patients.

trans-R-138727 Chemical Structure

CAS No. : 239466-74-1

Size	Price	Stock	Quantity
1 mg	USD 312	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 780	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 1250	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 2500	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 4060	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 6450	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Other Forms of trans-R-138727:

R-138727 Get quote
(R)-trans-138727-d₄ Get quote

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Purity & Documentation
References
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Description

Molecular Weight

349.42

Formula

C₁₈H₂₀FNO₃S

CAS No.

239466-74-1

Appearance

Solid

SMILES

O=C(O)/C=C1CN(C(C2=CC=CC=C2F)C(C3CC3)=O)CCC\1S

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hasegawa M, et al. Stereoselective inhibition of human platelet aggregation by R-138727, the active metabolite of CS-747 (prasugrel, LY640315), a novel P2Y12 receptor inhibitor. Thromb Haemost. 2005 Sep;94(3):593-8. [Content Brief]

trans-R-138727 Related Classifications

Cardiovascular Disease

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

trans-R-138727239466-74-1P2Y ReceptorInhibitorinhibitorinhibit

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