1. Immunology/Inflammation Vitamin D Related/Nuclear Receptor
  2. Glucocorticoid Receptor
  3. Triamcinolone acetonide-d6

Triamcinolone acetonide-d6 is deuterium labeled Triamcinolone acetonide.

For research use only. We do not sell to patients.

Triamcinolone acetonide-d<sub>6</sub> Chemical Structure

Triamcinolone acetonide-d6 Chemical Structure

CAS No. : 352431-33-5

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1 mg USD 580 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Triamcinolone acetonide-d6 is deuterium labeled Triamcinolone acetonide.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

440.53

Formula

C24H25D6FO6

CAS No.
Unlabeled CAS

76-25-5

Appearance

Solid

Color

White to off-white

SMILES

OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C(CC4)=CC(C=C5)=O)C)F)([H])C[C@@]1([H])OC(O2)(C([2H])([2H])[2H])C([2H])([2H])[2H])C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (113.50 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2700 mL 11.3500 mL 22.6999 mL
5 mM 0.4540 mL 2.2700 mL 4.5400 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2700 mL 11.3500 mL 22.6999 mL 56.7498 mL
5 mM 0.4540 mL 2.2700 mL 4.5400 mL 11.3500 mL
10 mM 0.2270 mL 1.1350 mL 2.2700 mL 5.6750 mL
15 mM 0.1513 mL 0.7567 mL 1.5133 mL 3.7833 mL
20 mM 0.1135 mL 0.5675 mL 1.1350 mL 2.8375 mL
25 mM 0.0908 mL 0.4540 mL 0.9080 mL 2.2700 mL
30 mM 0.0757 mL 0.3783 mL 0.7567 mL 1.8917 mL
40 mM 0.0567 mL 0.2837 mL 0.5675 mL 1.4187 mL
50 mM 0.0454 mL 0.2270 mL 0.4540 mL 1.1350 mL
60 mM 0.0378 mL 0.1892 mL 0.3783 mL 0.9458 mL
80 mM 0.0284 mL 0.1419 mL 0.2837 mL 0.7094 mL
100 mM 0.0227 mL 0.1135 mL 0.2270 mL 0.5675 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Triamcinolone acetonide-d6
Cat. No.:
HY-B0636S3
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