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Tricaine methanesulfonate  (Synonyms: MS-222)

Cat. No.: HY-W011777 Purity: 99.52%
SDS COA Handling Instructions

Molarity Calculator

Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures.

For research use only. We do not sell to patients.

Tricaine methanesulfonate Chemical Structure

Tricaine methanesulfonate Chemical Structure

CAS No. : 886-86-2

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
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Based on 5 publication(s) in Google Scholar

Other Forms of Tricaine methanesulfonate:

Tricaine methanesulfonate Related Antibodies

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  • Purity & Documentation

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Description

Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures[1].

In Vitro

Tricaine methanesulfonate in powder form easily can become airborne and could become hazardous to the handler[1].
Tricaine methanesulfonate (TMS) solution is photosensitive (its color changes with light exposure), although the color change does not necessarily indicate significant activity decrease and thus color should not be used to gauge degradation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tricaine methanesulfonate Related Antibodies
Molecular Weight

261.29

Formula

C10H15NO5S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OCC)C1=CC=CC(N)=C1.CS(=O)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (956.79 mM; Need ultrasonic)

DMSO : 100 mg/mL (382.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8272 mL 19.1358 mL 38.2716 mL
5 mM 0.7654 mL 3.8272 mL 7.6543 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.52%

SDS (393 KB)

COA (243 KB) HNMR (120 KB) RP-HPLC (95 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 3.8272 mL 19.1358 mL 38.2717 mL 95.6791 mL
5 mM 0.7654 mL 3.8272 mL 7.6543 mL 19.1358 mL
10 mM 0.3827 mL 1.9136 mL 3.8272 mL 9.5679 mL
15 mM 0.2551 mL 1.2757 mL 2.5514 mL 6.3786 mL
20 mM 0.1914 mL 0.9568 mL 1.9136 mL 4.7840 mL
25 mM 0.1531 mL 0.7654 mL 1.5309 mL 3.8272 mL
30 mM 0.1276 mL 0.6379 mL 1.2757 mL 3.1893 mL
40 mM 0.0957 mL 0.4784 mL 0.9568 mL 2.3920 mL
50 mM 0.0765 mL 0.3827 mL 0.7654 mL 1.9136 mL
60 mM 0.0638 mL 0.3189 mL 0.6379 mL 1.5947 mL
80 mM 0.0478 mL 0.2392 mL 0.4784 mL 1.1960 mL
100 mM 0.0383 mL 0.1914 mL 0.3827 mL 0.9568 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Tricaine methanesulfonate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tricaine886-86-2MS-222MS222MS 222OthersInhibitorinhibitorinhibit

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