2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species Tyrosinase
  4. Tyrosinase-IN-12

Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC50 value of 49.33 ± 2.64 µM and Ki value of 31.25 ± 0.25 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species (ROS) with an IC50 value of 25.39 ± 0.77 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors.

For research use only. We do not sell to patients.

Tyrosinase-IN-12 Chemical Structure

Tyrosinase-IN-12 Chemical Structure

CAS No. : 1860779-42-5

Size Price Stock Quantity
5 mg USD 123 In-stock
10 mg USD 198 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Tyrosinase-IN-12 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC50 value of 49.33 ± 2.64 µM and Ki value of 31.25 ± 0.25 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species (ROS) with an IC50 value of 25.39 ± 0.77 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors[1].

In Vitro

Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) (3day) is a potential anti-browning agent for fresh-cut fruits and vegetables[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tyrosinase-IN-12 Related Antibodies

Cell Viability Assay [1]

Cell Line: fresh-cut potato slices
Concentration:
Incubation Time: 3 day
Result: Exhibited browning inhibition effects close to those of kojic acid on fresh-cut potato slices.
Molecular Weight

313.80

Formula

C16H12ClN3S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

ClC1=CC=C(/C=N/NC2=NC(C3=CC=CC=C3)=CS2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (159.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1867 mL 15.9337 mL 31.8674 mL
5 mM 0.6373 mL 3.1867 mL 6.3735 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1867 mL 15.9337 mL 31.8674 mL 79.6686 mL
5 mM 0.6373 mL 3.1867 mL 6.3735 mL 15.9337 mL
10 mM 0.3187 mL 1.5934 mL 3.1867 mL 7.9669 mL
15 mM 0.2124 mL 1.0622 mL 2.1245 mL 5.3112 mL
20 mM 0.1593 mL 0.7967 mL 1.5934 mL 3.9834 mL
25 mM 0.1275 mL 0.6373 mL 1.2747 mL 3.1867 mL
30 mM 0.1062 mL 0.5311 mL 1.0622 mL 2.6556 mL
40 mM 0.0797 mL 0.3983 mL 0.7967 mL 1.9917 mL
50 mM 0.0637 mL 0.3187 mL 0.6373 mL 1.5934 mL
60 mM 0.0531 mL 0.2656 mL 0.5311 mL 1.3278 mL
80 mM 0.0398 mL 0.1992 mL 0.3983 mL 0.9959 mL
100 mM 0.0319 mL 0.1593 mL 0.3187 mL 0.7967 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Tyrosinase-IN-12 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tyrosinase-IN-121860779-42-5Reactive Oxygen SpeciesTyrosinasethiazolyl hydrazineanti-tyrosinaseantioxidantsanti-browningInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Tyrosinase-IN-12
Cat. No.:
HY-149404
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (251 KB) Français - FR (251 KB) Deutsch - DE (251 KB) Norwegian - NO (251 KB) Español - ES (251 KB) Swedish - SV (251 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.