2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. U-99194 maleate

U-99194 maleate  (Synonyms: U-99194A; PNU-99194A maleate; JPC-211 maleate)

Cat. No.: HY-12701A Purity: 99.23%
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U-99194 maleate is a potent and selective Dopamine3 Receptor (D3 receptor) antagonist. U-99194 maleate also enhances prolactin secretion and striatal dopamine synthesis.

For research use only. We do not sell to patients.

U-99194 maleate Chemical Structure

U-99194 maleate Chemical Structure

CAS No. : 234757-41-6

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5 mg USD 190 In-stock
10 mg USD 260 In-stock
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Based on 1 publication(s) in Google Scholar

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U-99194 maleate Related Antibodies

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Description

U-99194 maleate is a potent and selective Dopamine3 Receptor (D3 receptor) antagonist. U-99194 maleate also enhances prolactin secretion and striatal dopamine synthesis[1].

Molecular Weight

393.47

Formula

C21H31NO6
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

CCCN(CCC)C1CC2=C(C=C(OC)C(OC)=C2)C1.O=C(O)/C=C\C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (317.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5415 mL 12.7074 mL 25.4149 mL
5 mM 0.5083 mL 2.5415 mL 5.0830 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5415 mL 12.7074 mL 25.4149 mL 63.5372 mL
5 mM 0.5083 mL 2.5415 mL 5.0830 mL 12.7074 mL
10 mM 0.2541 mL 1.2707 mL 2.5415 mL 6.3537 mL
15 mM 0.1694 mL 0.8472 mL 1.6943 mL 4.2358 mL
20 mM 0.1271 mL 0.6354 mL 1.2707 mL 3.1769 mL
25 mM 0.1017 mL 0.5083 mL 1.0166 mL 2.5415 mL
30 mM 0.0847 mL 0.4236 mL 0.8472 mL 2.1179 mL
40 mM 0.0635 mL 0.3177 mL 0.6354 mL 1.5884 mL
50 mM 0.0508 mL 0.2541 mL 0.5083 mL 1.2707 mL
60 mM 0.0424 mL 0.2118 mL 0.4236 mL 1.0590 mL
80 mM 0.0318 mL 0.1588 mL 0.3177 mL 0.7942 mL
100 mM 0.0254 mL 0.1271 mL 0.2541 mL 0.6354 mL
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U-99194 maleate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

U-99194234757-41-6U-99194APNU-99194AJPC-211U99194U 99194JPC211JPC 211Dopamine ReceptorD3 ReceptorAntagonist5-HT1AInhibitorinhibitorinhibit

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