2. Protein Tyrosine Kinase/RTK
  3. Ephrin Receptor
  4. UniPR129

UniPR129 is a potent Eph/ephrin antagonist with IC50s of 0.84-3.01 μM. UniPR129 has the potential for the research of cancer disease.

For research use only. We do not sell to patients.

UniPR129 Chemical Structure

UniPR129 Chemical Structure

CAS No. : 1639159-47-9

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5 mg USD 280 In-stock
10 mg USD 450 In-stock
25 mg USD 890 In-stock
50 mg USD 1450 In-stock
100 mg USD 2300 In-stock
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500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

UniPR129 Related Antibodies

Top Publications Citing Use of Products

View All Ephrin Receptor Isoform Specific Products:

View All Isoforms
EphA2 EphA3 EphA4

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

UniPR129 is a potent Eph/ephrin antagonist with IC50s of 0.84-3.01 μM. UniPR129 has the potential for the research of cancer disease[1][2].

IC50 & Target[2]

EphA1

1.39 μM (IC50)

EphA2

1.12 μM (IC50)

EphA3

1.43 μM (IC50)

EphA4

1.58 μM (IC50)

EphA5

1.57 μM (IC50)

EphA6

1.53 μM (IC50)

EphA7

1.24 μM (IC50)

EphA8

0.84 μM (IC50)

EphB1

2.75 μM (IC50)

EphB2

2.96 μM (IC50)

EphB3

3.74 μM (IC50)

EphB4

2.60 μM (IC50)

EphB5

3.01 μM (IC50)

Molecular Weight

576.81

Formula

C36H52N2O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(N[C@H](CC(O)=O)CC3=CNC4=CC=CC=C34)=O)([H])[C@@]5([H])[C@]([C@@]6([C@](C[C@H](O)CC6)([H])CC5)C)([H])CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (57.78 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7337 mL 8.6684 mL 17.3367 mL
5 mM 0.3467 mL 1.7337 mL 3.4673 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7337 mL 8.6684 mL 17.3367 mL 43.3418 mL
5 mM 0.3467 mL 1.7337 mL 3.4673 mL 8.6684 mL
10 mM 0.1734 mL 0.8668 mL 1.7337 mL 4.3342 mL
15 mM 0.1156 mL 0.5779 mL 1.1558 mL 2.8895 mL
20 mM 0.0867 mL 0.4334 mL 0.8668 mL 2.1671 mL
25 mM 0.0693 mL 0.3467 mL 0.6935 mL 1.7337 mL
30 mM 0.0578 mL 0.2889 mL 0.5779 mL 1.4447 mL
40 mM 0.0433 mL 0.2167 mL 0.4334 mL 1.0835 mL
50 mM 0.0347 mL 0.1734 mL 0.3467 mL 0.8668 mL
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UniPR129 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UniPR1291639159-47-9UniPR 129UniPR-129Ephrin ReceptorEph/ephrincancerInhibitorinhibitorinhibit

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