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  4. VCC234718

VCC234718 is a molecule with mycobacterial growth inhibitory activity, specifically targeting Mycobacterium tuberculosis (Mtb). The primary molecular target of VCC234718 is inosine monophosphate dehydrogenase (GuaB2), and it inhibits the growth of Mtb by affecting the function of this enzyme. VCC234718 inhibits GuaB2 with a K value of 100 nM and exhibits non-competitive inhibition with IMP and NAD+. VCC234718 exerts its inhibitory effect by directly interacting with IMP and binding at the NAD+ site.

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VCC234718 Chemical Structure

VCC234718 Chemical Structure

CAS No. : 1278553-16-4

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VCC234718 Related Antibodies

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Description

VCC234718 is a molecule with mycobacterial growth inhibitory activity, specifically targeting Mycobacterium tuberculosis (Mtb). The primary molecular target of VCC234718 is inosine monophosphate dehydrogenase (GuaB2), and it inhibits the growth of Mtb by affecting the function of this enzyme. VCC234718 inhibits GuaB2 with a K value of 100 nM and exhibits non-competitive inhibition with IMP and NAD+. VCC234718 exerts its inhibitory effect by directly interacting with IMP and binding at the NAD+ site[1].

Molecular Weight

387.50

Formula

C20H25N3O3S
CAS No.
SMILES

O=C(N1CCN(CC1)S(=O)(C2=CC=CC3=C2C=CN=C3)=O)C4CCCCC4
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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VCC234718 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VCC2347181278553-16-4VCC 234718VCC-234718OthersInhibitorinhibitorinhibit

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