2. Antibody-drug Conjugate/ADC Related
  3. ADC Antibody
  4. Vobramitamab

Vobramitamab  (Synonyms: AEX-4089)

Cat. No.: HY-P99101 Purity: 99.67%
COA

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Vobramitamab is a humanized B7-H3 monoclonal antibody (mAb). Vobramitamab conjugated with prodrug seco-DUBA (HY-132180A) via a cleavable linker, to form antibody-drug conjugate (ADC), the MGC018. .

For research use only. We do not sell to patients.

CAS No. : 2490556-50-6

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1 mg USD 400 In-stock
5 mg USD 1120 In-stock
10 mg USD 1800 In-stock
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Based on 1 publication(s) in Google Scholar

Vobramitamab Related Antibodies

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Description

Vobramitamab is a humanized B7-H3 monoclonal antibody (mAb). Vobramitamab conjugated with prodrug seco-DUBA (HY-132180A) via a cleavable linker, to form antibody-drug conjugate (ADC), the MGC018. [1][2][3].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Humanized
IC50 & Target

B7-H3
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Vobramitamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Loaded Vobramitamab on AHC2 biosensor, can bind CD276/B7-H3 Protein, Mouse (HEK293, His，HY-P7639) with an affinity constant of 1.825E-09 M as determined in BLI assay.
Purity & Documentation

Purity: 99.67%

COA (231 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Vobramitamab Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vobramitamab2490556-50-6AEX-4089AEX4089AEX 4089ADC Antibodycleavable linkerantibody-drug conjugate (ADC)Inhibitorinhibitorinhibit

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