1. Neuronal Signaling
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  3. W-13 hydrochloride

W-13 hydrochloride is a calmodulin antagonist. W-13 hydrochloride can inhibit Tamoxifen (HY-13757A)-resistant human breast cancer cell growth.

For research use only. We do not sell to patients.

W-13 hydrochloride Chemical Structure

W-13 hydrochloride Chemical Structure

CAS No. : 88519-57-7

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Description

W-13 hydrochloride is a calmodulin antagonist. W-13 hydrochloride can inhibit Tamoxifen (HY-13757A)-resistant human breast cancer cell growth[1].

Molecular Weight

349.28

Formula

C14H18Cl2N2O2S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=C2C(Cl)=CC=CC2=C1)(NCCCCN)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (357.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8630 mL 14.3152 mL 28.6303 mL
5 mM 0.5726 mL 2.8630 mL 5.7261 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8630 mL 14.3152 mL 28.6303 mL 71.5758 mL
5 mM 0.5726 mL 2.8630 mL 5.7261 mL 14.3152 mL
10 mM 0.2863 mL 1.4315 mL 2.8630 mL 7.1576 mL
15 mM 0.1909 mL 0.9543 mL 1.9087 mL 4.7717 mL
20 mM 0.1432 mL 0.7158 mL 1.4315 mL 3.5788 mL
25 mM 0.1145 mL 0.5726 mL 1.1452 mL 2.8630 mL
30 mM 0.0954 mL 0.4772 mL 0.9543 mL 2.3859 mL
40 mM 0.0716 mL 0.3579 mL 0.7158 mL 1.7894 mL
50 mM 0.0573 mL 0.2863 mL 0.5726 mL 1.4315 mL
60 mM 0.0477 mL 0.2386 mL 0.4772 mL 1.1929 mL
80 mM 0.0358 mL 0.1789 mL 0.3579 mL 0.8947 mL
100 mM 0.0286 mL 0.1432 mL 0.2863 mL 0.7158 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
W-13 hydrochloride
Cat. No.:
HY-100910
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