2. Stem Cell/Wnt
  3. Wnt
  4. Wnt pathway inhibitor 4

Wnt pathway inhibitor 4 (compound 16D) is an anticancer agent that has anti-proliferative activity.

For research use only. We do not sell to patients.

Wnt pathway inhibitor 4 Chemical Structure

Wnt pathway inhibitor 4 Chemical Structure

CAS No. : 663214-57-1

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Based on 1 publication(s) in Google Scholar

Wnt pathway inhibitor 4 Related Antibodies

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Description

Wnt pathway inhibitor 4 (compound 16D) is an anticancer agent that has anti-proliferative activity[1].

Cellular Effect
Cell Line Type Value Description References
A-375 IC50
23.3 nM
Compound: 16d
Antiproliferative activity against human A375 cells after 72 hrs by MTS assay
Antiproliferative activity against human A375 cells after 72 hrs by MTS assay
[PMID: 30099258]
In Vitro

Wnt pathway inhibitor 4 (Compound 16D) (72 h) inhibits proliferation of human A375 melanoma cells (IC50: 23.3 nM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Wnt pathway inhibitor 4 Related Antibodies
Molecular Weight

431.24

Formula

C19H15BrN2O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N#CC1=C(N)OC2=C(C1C3=CC(Br)=C(C(OC)=C3)OC)C=C4OCOC4=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 16.67 mg/mL (38.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3189 mL 11.5945 mL 23.1889 mL
5 mM 0.4638 mL 2.3189 mL 4.6378 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3189 mL 11.5945 mL 23.1889 mL 57.9724 mL
5 mM 0.4638 mL 2.3189 mL 4.6378 mL 11.5945 mL
10 mM 0.2319 mL 1.1594 mL 2.3189 mL 5.7972 mL
15 mM 0.1546 mL 0.7730 mL 1.5459 mL 3.8648 mL
20 mM 0.1159 mL 0.5797 mL 1.1594 mL 2.8986 mL
25 mM 0.0928 mL 0.4638 mL 0.9276 mL 2.3189 mL
30 mM 0.0773 mL 0.3865 mL 0.7730 mL 1.9324 mL
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Wnt pathway inhibitor 4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Wnt pathway inhibitor 4663214-57-1Wnt pathway inhibitor4Wnt pathway inhibitor-4WntCanceranti-proliferativemicrotubuleInhibitorinhibitorinhibit

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