2. Stem Cell/Wnt
  3. Wnt
  4. Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates Wnt/β-catenin signal transmission.

For research use only. We do not sell to patients.

Wnt/β-catenin agonist 4 Chemical Structure

Wnt/β-catenin agonist 4 Chemical Structure

CAS No. : 912784-79-3

Size Price Stock Quantity
5 mg USD 80 In-stock
10 mg USD 130 In-stock
25 mg USD 250 In-stock
50 mg USD 400 In-stock
100 mg USD 650 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Wnt/β-catenin agonist 4 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Wnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates Wnt/β-catenin signal transmission[1].

IC50 & Target

Wnt[1]
In Vitro

Wnt/β-catenin agonist 4 (Derivative 83) (120 μM; 24 h) shows 1049% β-catenin activity in HEK293 and SW480 cells[1].
Wnt/β-catenin agonist 4 (11 μM; 4 days) shows 2848% ALP activity on differentiation of ST2 cell line into osteoblasts[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Wnt/β-catenin agonist 4 Related Antibodies
Molecular Weight

314.31

Formula

C16H15FN4O2
CAS No.
Appearance

Solid

Color

Yellow to brown

SMILES

O=C(C1=NOC(C2=CC=C(F)C=C2)=C1)NCCCN3C=CN=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (397.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1816 mL 15.9079 mL 31.8157 mL
5 mM 0.6363 mL 3.1816 mL 6.3631 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1816 mL 15.9079 mL 31.8157 mL 79.5393 mL
5 mM 0.6363 mL 3.1816 mL 6.3631 mL 15.9079 mL
10 mM 0.3182 mL 1.5908 mL 3.1816 mL 7.9539 mL
15 mM 0.2121 mL 1.0605 mL 2.1210 mL 5.3026 mL
20 mM 0.1591 mL 0.7954 mL 1.5908 mL 3.9770 mL
25 mM 0.1273 mL 0.6363 mL 1.2726 mL 3.1816 mL
30 mM 0.1061 mL 0.5303 mL 1.0605 mL 2.6513 mL
40 mM 0.0795 mL 0.3977 mL 0.7954 mL 1.9885 mL
50 mM 0.0636 mL 0.3182 mL 0.6363 mL 1.5908 mL
60 mM 0.0530 mL 0.2651 mL 0.5303 mL 1.3257 mL
80 mM 0.0398 mL 0.1988 mL 0.3977 mL 0.9942 mL
100 mM 0.0318 mL 0.1591 mL 0.3182 mL 0.7954 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Wnt/β-catenin agonist 4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Wnt/β-catenin agonist 4912784-79-3Wntβ-cateninWnt/β-catenin signal transmissionHEK293osteoblastsSW480Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Wnt/β-catenin agonist 4
Cat. No.:
HY-151520
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.