WP9QY

Cat. No.: HY-P2612: FAQs
Data Sheet Handling Instructions

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WP9QY, TNF-a Antagonist, TNF-a Antagonist is a biological active peptide. (This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.)

For research use only. We do not sell to patients.

Custom Peptide Synthesis

WP9QY Chemical Structure

CAS No. : 199999-60-5

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This product is a controlled substance and not for sale in your territory.

Other Forms of WP9QY:

WP9QY TFA Get quote

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TNFRSF1A/CD120a TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

Biological Activity
Purity & Documentation
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Description	WP9QY, TNF-a Antagonist, TNF-a Antagonist is a biological active peptide. (This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.)
Molecular Weight	1226.38
Formula	C₅₈H₇₁N₁₁O₁₅S₂
CAS No.	199999-60-5
Sequence	Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr (Disulfide bridge:Cys2-Cys8)
Sequence Shortening	YCWSQYLCY (Disulfide bridge:Cys2-Cys8)
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (257 KB) Handling Instructions (2659 KB)
References	[1]. Lin CC, et al. Functional PEG-peptide hydrogels to modulate local inflammation induced by the pro-inflammatory cytokine TNFalpha. Biomaterials. 2009 Oct;30(28):4907-14. [Content Brief]

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Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WP9QY199999-60-5TNF ReceptorTumor Necrosis Factor ReceptorTNFRInhibitorinhibitorinhibit

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