2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. Xanthopterin hydrate

Xanthopterin hydrate, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm. Xanthopterin hydrate(XPT) causes renal growth and hypertrophy in rat. Xanthopterin hydrate inhibits RNA synthesis.

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Xanthopterin hydrate Chemical Structure

Xanthopterin hydrate Chemical Structure

CAS No. : 5979-01-1

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

Other Forms of Xanthopterin hydrate:

Xanthopterin hydrate Related Antibodies

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Description

Xanthopterin hydrate, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm[2]. Xanthopterin hydrate(XPT) causes renal growth and hypertrophy in rat[1]. Xanthopterin hydrate inhibits RNA synthesis[4].

In Vitro

Xanthopterin (7.8-250 mM; 24 hours) show a significant reduction in mitochondrial activity with respect to controls (IC50=109 mM)[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Xanthopterin hydrate Related Antibodies

Cell Viability Assay[2]

Cell Line: MCF-7 cells
Concentration: 7.8 mM-250 mM
Incubation Time: 24 hours
Result: Resulted in a reduction in mitochondrial activity.
Molecular Weight

197.15

Formula

C6H7N5O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1NC(N)=NC2=C1NC(C=N2)=O.O
Structure Classification
Initial Source

the yellow granule in the Oriental hornet bear wings
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (25.36 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0723 mL 25.3614 mL 50.7228 mL
5 mM 1.0145 mL 5.0723 mL 10.1446 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

SDS (393 KB)

COA (250 KB) HNMR (247 KB) MS (70 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.0723 mL 25.3614 mL 50.7228 mL 126.8070 mL
5 mM 1.0145 mL 5.0723 mL 10.1446 mL 25.3614 mL
10 mM 0.5072 mL 2.5361 mL 5.0723 mL 12.6807 mL
15 mM 0.3382 mL 1.6908 mL 3.3815 mL 8.4538 mL
20 mM 0.2536 mL 1.2681 mL 2.5361 mL 6.3404 mL
25 mM 0.2029 mL 1.0145 mL 2.0289 mL 5.0723 mL
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Xanthopterin hydrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Xanthopterin5979-01-1DNA/RNA SynthesisInhibitorinhibitorinhibit

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