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  3. Drug Intermediate
  4. XL388-C2-amide-PEG9-NH2 TFA

XL388-C2-amide-PEG9-NH2 TFA is an intermediate used in the synthesis of C26-linked Rapamycin analog.

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XL388-C2-amide-PEG9-NH2 TFA Chemical Structure

XL388-C2-amide-PEG9-NH2 TFA Chemical Structure

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Other Forms of XL388-C2-amide-PEG9-NH2 TFA:

XL388-C2-amide-PEG9-NH2 TFA Related Antibodies

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Description

XL388-C2-amide-PEG9-NH2 TFA is an intermediate used in the synthesis of C26-linked Rapamycin analog[1].

Molecular Weight

1022.06

Formula

C45H63F4N5O15S
Appearance

Oil

Color

Colorless to light yellow

SMILES

O=C(NCCS(=O)(C1=CC=C(C(N2CCOC3=CC=C(C4=CC=C(N)N=C4)C=C3C2)=O)C(C)=C1F)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN.OC(C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (97.84 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9784 mL 4.8921 mL 9.7842 mL
5 mM 0.1957 mL 0.9784 mL 1.9568 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9784 mL 4.8921 mL 9.7842 mL 24.4604 mL
5 mM 0.1957 mL 0.9784 mL 1.9568 mL 4.8921 mL
10 mM 0.0978 mL 0.4892 mL 0.9784 mL 2.4460 mL
15 mM 0.0652 mL 0.3261 mL 0.6523 mL 1.6307 mL
20 mM 0.0489 mL 0.2446 mL 0.4892 mL 1.2230 mL
25 mM 0.0391 mL 0.1957 mL 0.3914 mL 0.9784 mL
30 mM 0.0326 mL 0.1631 mL 0.3261 mL 0.8153 mL
40 mM 0.0245 mL 0.1223 mL 0.2446 mL 0.6115 mL
50 mM 0.0196 mL 0.0978 mL 0.1957 mL 0.4892 mL
60 mM 0.0163 mL 0.0815 mL 0.1631 mL 0.4077 mL
80 mM 0.0122 mL 0.0612 mL 0.1223 mL 0.3058 mL
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XL388-C2-amide-PEG9-NH2 TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XL388-C2-amide-PEG9-NH2Drug IntermediateDrug IintermediateintermediateRapamycin analogsynthesisC26-linkedInhibitorinhibitorinhibit

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