2. Metabolic Enzyme/Protease
  3. Proteasome
  4. Z-Ala-Arg-Arg-AMC

Z-Ala-Arg-Arg-AMC  (Synonyms: Fluorogenic Proteasome Substrate; Z-ARR-AMC)

Cat. No.: HY-134961 Purity: 98.00%
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Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Z-Ala-Arg-Arg-AMC Chemical Structure

Z-Ala-Arg-Arg-AMC Chemical Structure

CAS No. : 90468-18-1

Size Price Stock Quantity
1 mg USD 52 In-stock
5 mg USD 130 In-stock
10 mg USD 200 In-stock
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Z-Ala-Arg-Arg-AMC Related Antibodies

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Description

Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome[1].

Molecular Weight

692.77

Formula

C33H44N10O7
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Z-Ala-Arg-Arg-AMC
Sequence Shortening

Z-ARR-AMC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (72.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4435 mL 7.2174 mL 14.4348 mL
5 mM 0.2887 mL 1.4435 mL 2.8870 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4435 mL 7.2174 mL 14.4348 mL 36.0870 mL
5 mM 0.2887 mL 1.4435 mL 2.8870 mL 7.2174 mL
10 mM 0.1443 mL 0.7217 mL 1.4435 mL 3.6087 mL
15 mM 0.0962 mL 0.4812 mL 0.9623 mL 2.4058 mL
20 mM 0.0722 mL 0.3609 mL 0.7217 mL 1.8044 mL
25 mM 0.0577 mL 0.2887 mL 0.5774 mL 1.4435 mL
30 mM 0.0481 mL 0.2406 mL 0.4812 mL 1.2029 mL
40 mM 0.0361 mL 0.1804 mL 0.3609 mL 0.9022 mL
50 mM 0.0289 mL 0.1443 mL 0.2887 mL 0.7217 mL
60 mM 0.0241 mL 0.1203 mL 0.2406 mL 0.6015 mL
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Z-Ala-Arg-Arg-AMC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-Ala-Arg-Arg-AMC90468-18-1Fluorogenic Proteasome Substrate Z-ARR-AMCProteasometrypsin-likeproteasomeInhibitorinhibitorinhibit

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