1. Metabolic Enzyme/Protease
  2. Prolyl Endopeptidase (PREP)
  3. Z-Gly-Pro-pNA

Z-Gly-Pro-pNA is a substrate for measuring prolyl endopeptidase (PEP) inhibitory activity.

For research use only. We do not sell to patients.

Z-Gly-Pro-pNA Chemical Structure

Z-Gly-Pro-pNA Chemical Structure

CAS No. : 65022-15-3

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
25 mg In-stock
50 mg In-stock
100 mg In-stock
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500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Z-Gly-Pro-pNA is a substrate for measuring prolyl endopeptidase (PEP) inhibitory activity[1].

Molecular Weight

426.42

Formula

C21H22N4O6

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@H](CCC1)N1C(CNC(OCC2=CC=CC=C2)=O)=O)NC(C=C3)=CC=C3[N](=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 175 mg/mL (410.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3451 mL 11.7255 mL 23.4511 mL
5 mM 0.4690 mL 2.3451 mL 4.6902 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3451 mL 11.7255 mL 23.4511 mL 58.6276 mL
5 mM 0.4690 mL 2.3451 mL 4.6902 mL 11.7255 mL
10 mM 0.2345 mL 1.1726 mL 2.3451 mL 5.8628 mL
15 mM 0.1563 mL 0.7817 mL 1.5634 mL 3.9085 mL
20 mM 0.1173 mL 0.5863 mL 1.1726 mL 2.9314 mL
25 mM 0.0938 mL 0.4690 mL 0.9380 mL 2.3451 mL
30 mM 0.0782 mL 0.3909 mL 0.7817 mL 1.9543 mL
40 mM 0.0586 mL 0.2931 mL 0.5863 mL 1.4657 mL
50 mM 0.0469 mL 0.2345 mL 0.4690 mL 1.1726 mL
60 mM 0.0391 mL 0.1954 mL 0.3909 mL 0.9771 mL
80 mM 0.0293 mL 0.1466 mL 0.2931 mL 0.7328 mL
100 mM 0.0235 mL 0.1173 mL 0.2345 mL 0.5863 mL
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Z-Gly-Pro-pNA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Z-Gly-Pro-pNA
Cat. No.:
HY-137220
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