2. Apoptosis
  3. Apoptosis
  4. (Z)-Indirubin

(Z)-Indirubin  (Synonyms: (Z)-Couroupitine B; (Z)-Indigo red; (Z)-Indigopurpurin)

Cat. No.: HY-N0117A Purity: 99.66%
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(Z)-Indirubin is an isomer of Indirubin (HY-N0117). Indirubin is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia.

For research use only. We do not sell to patients.

(Z)-Indirubin Chemical Structure

(Z)-Indirubin Chemical Structure

CAS No. : 906748-38-7

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Based on 1 publication(s) in Google Scholar

Other Forms of (Z)-Indirubin:

(Z)-Indirubin Related Antibodies

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Description

(Z)-Indirubin is an isomer of Indirubin (HY-N0117). Indirubin is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia[1].

Molecular Weight

262.26

Formula

C16H10N2O2
CAS No.
Appearance

Solid

Color

Dark purple to black

SMILES

O=C1/C(C2=CC=CC=C2N1)=C3NC4=CC=CC=C4C\3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 4.17 mg/mL (15.90 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8130 mL 19.0650 mL 38.1301 mL
5 mM 0.7626 mL 3.8130 mL 7.6260 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8130 mL 19.0650 mL 38.1301 mL 95.3252 mL
5 mM 0.7626 mL 3.8130 mL 7.6260 mL 19.0650 mL
10 mM 0.3813 mL 1.9065 mL 3.8130 mL 9.5325 mL
15 mM 0.2542 mL 1.2710 mL 2.5420 mL 6.3550 mL
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(Z)-Indirubin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Z)-Indirubin906748-38-7(Z)-Couroupitine B (Z)-Indigo red (Z)-IndigopurpurinApoptosisAlkaloidisomerCouroupitine BleukemiaInhibitorinhibitorinhibit

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