1. Metabolic Enzyme/Protease
  2. Cathepsin
  3. Z-Phe-Arg-pNA

Z-Phe-Arg-pNA is a substrate of Cathepsin L.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Z-Phe-Arg-pNA Chemical Structure

Z-Phe-Arg-pNA Chemical Structure

CAS No. : 117761-01-0

Size Price Stock Quantity
5 mg USD 85 In-stock
10 mg USD 135 In-stock
25 mg USD 285 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Z-Phe-Arg-pNA is a substrate of Cathepsin L[1].

IC50 & Target

Cathepsin L[1]

Molecular Weight

575.62

Formula

C29H33N7O6

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Cbz}-Phe-Arg-{pNA}

Sequence Shortening

{Cbz}-FR-{pNA}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 17 mg/mL (29.53 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7373 mL 8.6863 mL 17.3726 mL
5 mM 0.3475 mL 1.7373 mL 3.4745 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7373 mL 8.6863 mL 17.3726 mL 43.4314 mL
5 mM 0.3475 mL 1.7373 mL 3.4745 mL 8.6863 mL
10 mM 0.1737 mL 0.8686 mL 1.7373 mL 4.3431 mL
15 mM 0.1158 mL 0.5791 mL 1.1582 mL 2.8954 mL
20 mM 0.0869 mL 0.4343 mL 0.8686 mL 2.1716 mL
25 mM 0.0695 mL 0.3475 mL 0.6949 mL 1.7373 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Z-Phe-Arg-pNA
Cat. No.:
HY-P4515
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