2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK
  4. Zemprocitinib

Zemprocitinib (Compound 1) is a Janus kinase (JAK) inhibitor. The IC50 values for JAK1, JAK2 and TYK2 are 5.95, 141.3 and 119 nM, respectively.

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Zemprocitinib Chemical Structure

Zemprocitinib Chemical Structure

CAS No. : 2417414-44-7

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Zemprocitinib Related Antibodies

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JAK1 JAK2 JAK3 Tyk2 JAK

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Description

Zemprocitinib (Compound 1) is a Janus kinase (JAK) inhibitor. The IC50 values for JAK1, JAK2 and TYK2 are 5.95, 141.3 and 119 nM, respectively[1].

IC50 & Target

JAK1

5.95 nM (IC50)

JAK2

141.3 nM (IC50)

Tyk2

119 nM (IC50)

Molecular Weight

345.42

Formula

C16H19N5O2S
CAS No.
SMILES

O=S(NC12CC(C1)(C2)N3C=NC4=CNC5=NC=CC5=C43)(CCC)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Zemprocitinib Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zemprocitinib2417414-44-7JAKJanus kinaseInhibitorinhibitorinhibit

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