Zuclomiphene citrate

Cat. No.: HY-B1617A Purity: 98.09%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Zuclomiphene citrate is a cis isomer of Clomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent.

For research use only. We do not sell to patients.

Zuclomiphene citrate Chemical Structure

CAS No. : 7619-53-6

Size	Price	Stock	Quantity
5 mg	USD 680	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 1080	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Zuclomiphene citrate:

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Estrogen Receptor/ERR

Molecular Weight

598.08

Formula

C₃₂H₃₆ClNO₈

CAS No.

7619-53-6

Appearance

Solid

Color

White to off-white

SMILES

Cl/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(CC)CC)C=C2)/C3=CC=CC=C3.O=C(CC(C(O)=O)(O)CC(O)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (167.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6720 mL	8.3601 mL	16.7202 mL
5 mM	0.3344 mL	1.6720 mL	3.3440 mL
10 mM	0.1672 mL	0.8360 mL	1.6720 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.09%

Select Batch:

Data Sheet (276 KB) SDS (251 KB)

COA (255 KB) HNMR (141 KB) RP-HPLC (243 KB) Elemental Analysis Report (113 KB)

Handling Instructions (2659 KB)

References

[1]. Fontenot GK, et al. Differential effects of isomers of clomiphene citrate on reproductive tissues in male mice. BJU Int. 2016 Feb;117(2):344-50. [Content Brief]

[2]. Mikkelson TJ, et al. Single-dose pharmacokinetics of clomiphene citrate in normal volunteers. Fertil Steril. 1986 Sep;46(3):392-6. [Content Brief]

[3]. Sutherland RL. Estrogen antagonists in chick oviduct: antagonist activity of eight synthetic triphenylethylene derivatives and their interactions with cytoplasmic and nuclear estrogen receptors. Endocrinology. 1981 Dec;109(6):2061-8. [Content Brief]

[4]. Ramsey RB, et al. The biochemical and morphological response of hydrolytic enzymes in the developing brain to hypocholesterolemic agents. Acta Neuropathol. 1980;49(2):89-94. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6720 mL	8.3601 mL	16.7202 mL	41.8004 mL
	5 mM	0.3344 mL	1.6720 mL	3.3440 mL	8.3601 mL
	10 mM	0.1672 mL	0.8360 mL	1.6720 mL	4.1800 mL
	15 mM	0.1115 mL	0.5573 mL	1.1147 mL	2.7867 mL
	20 mM	0.0836 mL	0.4180 mL	0.8360 mL	2.0900 mL
	25 mM	0.0669 mL	0.3344 mL	0.6688 mL	1.6720 mL
	30 mM	0.0557 mL	0.2787 mL	0.5573 mL	1.3933 mL
	40 mM	0.0418 mL	0.2090 mL	0.4180 mL	1.0450 mL
	50 mM	0.0334 mL	0.1672 mL	0.3344 mL	0.8360 mL
	60 mM	0.0279 mL	0.1393 mL	0.2787 mL	0.6967 mL
	80 mM	0.0209 mL	0.1045 mL	0.2090 mL	0.5225 mL
	100 mM	0.0167 mL	0.0836 mL	0.1672 mL	0.4180 mL