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  5. β-N-methylamino-L-alanine hydrochloride

β-N-methylamino-L-alanine hydrochloride  (Synonyms: BMAA hydrochloride)

Cat. No.: HY-W015546 Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

β-N-methylamino-L-alanine hydrochloride (BMAA hydrochloride) is a neurotoxin produced by cyanobacteria. β-N-methylamino-L-alanine hydrochloride could cause amyotrophic lateral sclerosis (ALS) and possibly other neurodegenerative diseases.

For research use only. We do not sell to patients.

β-N-methylamino-L-alanine hydrochloride Chemical Structure

β-N-methylamino-L-alanine hydrochloride Chemical Structure

CAS No. : 16012-55-8

Size Price Stock Quantity
5 mg USD 50 In-stock
10 mg USD 65 In-stock
50 mg USD 135 In-stock
100 mg USD 215 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

β-N-methylamino-L-alanine hydrochloride Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE β-N-methylamino-L-alanine hydrochloride

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

β-N-methylamino-L-alanine hydrochloride (BMAA hydrochloride) is a neurotoxin produced by cyanobacteria. β-N-methylamino-L-alanine hydrochloride could cause amyotrophic lateral sclerosis (ALS) and possibly other neurodegenerative diseases[1][2][3].

Molecular Weight

154.60

Formula

C4H11ClN2O2
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

N[C@@H](CNC)C(O)=O.[H]Cl
Structure Classification
Initial Source

cyanobacteria
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 31.25 mg/mL (202.13 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.4683 mL 32.3415 mL 64.6831 mL
5 mM 1.2937 mL 6.4683 mL 12.9366 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (161.71 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (248 KB) HNMR (214 KB) MS (71 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.4683 mL 32.3415 mL 64.6831 mL 161.7076 mL
5 mM 1.2937 mL 6.4683 mL 12.9366 mL 32.3415 mL
10 mM 0.6468 mL 3.2342 mL 6.4683 mL 16.1708 mL
15 mM 0.4312 mL 2.1561 mL 4.3122 mL 10.7805 mL
20 mM 0.3234 mL 1.6171 mL 3.2342 mL 8.0854 mL
25 mM 0.2587 mL 1.2937 mL 2.5873 mL 6.4683 mL
30 mM 0.2156 mL 1.0781 mL 2.1561 mL 5.3903 mL
40 mM 0.1617 mL 0.8085 mL 1.6171 mL 4.0427 mL
50 mM 0.1294 mL 0.6468 mL 1.2937 mL 3.2342 mL
60 mM 0.1078 mL 0.5390 mL 1.0781 mL 2.6951 mL
80 mM 0.0809 mL 0.4043 mL 0.8085 mL 2.0213 mL
100 mM 0.0647 mL 0.3234 mL 0.6468 mL 1.6171 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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β-N-methylamino-L-alanine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-N-methylamino-L-alanine16012-55-8BMAAOthersneurotoxincyanobacteriaamyotrophiclateralsclerosisALSneurodegenerativediseasesInhibitorinhibitorinhibit

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