1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one

Cat. No.: HY-W081348 Purity: 99.54%: Data Sheet
SDS

COA
Handling Instructions Technical Support

1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one (Compound 2) has antiprion activity in ScN2a and F3 cells with IC₅₀ values of 13 nM and 25 nM, respectively.

For research use only. We do not sell to patients.

1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one Chemical Structure

CAS No. : 60798-06-3

Size	Price	Stock	Quantity
25 mg	USD 37	In-stock	Estimated Time of Arrival: June 3
50 mg	USD 60	In-stock	Estimated Time of Arrival: June 3
100 mg	USD 99	In-stock	Estimated Time of Arrival: June 3
250 mg	USD 182	In-stock	Estimated Time of Arrival: June 3
500 mg	USD 255	In-stock	Estimated Time of Arrival: June 3
1 g	USD 360	In-stock	Estimated Time of Arrival: June 3
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10 g		Get quote

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Description

1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one (Compound 2) has antiprion activity in ScN2a and F3 cells with IC₅₀ values of 13 nM and 25 nM, respectively^[1].

Molecular Weight

204.23

Formula

C₁₁H₁₂N₂O₂

CAS No.

60798-06-3

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1CC(C)=NN1C2=CC=C(OC)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Purity & Documentation

Purity: 99.54%

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Data Sheet (267 KB) SDS (393 KB)

COA (248 KB) HNMR (213 KB) RP-HPLC (362 KB)

Handling Instructions (2659 KB)

References

[1]. Kimata A, et al. New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation. J Med Chem. 2007 Oct 18;50(21):5053-6. [Content Brief]