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  4. 17β-HSD1-IN-1

17β-HSD1-IN-1 (Compound 1) is a highly selective 17β-HSD1 inhibitor with IC50s of 5.6 and 3155 nM for 17β-HSD1 and 17β-HSD2, respectively. 17β-HSD1-IN-1 can be used for the research of non-small cell lung cancer (NSCLC).

For research use only. We do not sell to patients.

17β-HSD1-IN-1 Chemical Structure

17β-HSD1-IN-1 Chemical Structure

CAS No. : 2760791-96-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO USD 195 In-stock
Solid
5 mg USD 264 In-stock
10 mg USD 423 In-stock
25 mg USD 890 In-stock
50 mg USD 1425 In-stock
100 mg USD 2280 In-stock
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Based on 1 publication(s) in Google Scholar

17β-HSD1-IN-1 Related Antibodies

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Description

17β-HSD1-IN-1 (Compound 1) is a highly selective 17β-HSD1 inhibitor with IC50s of 5.6 and 3155 nM for 17β-HSD1 and 17β-HSD2, respectively. 17β-HSD1-IN-1 can be used for the research of non-small cell lung cancer (NSCLC)[1].

Molecular Weight

335.40

Formula

C21H21NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1=CC=CC=C1N(C(C2=CC=C(O2)C3=CC(C)=C(C(C)=C3)O)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (298.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9815 mL 14.9076 mL 29.8151 mL
5 mM 0.5963 mL 2.9815 mL 5.9630 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9815 mL 14.9076 mL 29.8151 mL 74.5379 mL
5 mM 0.5963 mL 2.9815 mL 5.9630 mL 14.9076 mL
10 mM 0.2982 mL 1.4908 mL 2.9815 mL 7.4538 mL
15 mM 0.1988 mL 0.9938 mL 1.9877 mL 4.9692 mL
20 mM 0.1491 mL 0.7454 mL 1.4908 mL 3.7269 mL
25 mM 0.1193 mL 0.5963 mL 1.1926 mL 2.9815 mL
30 mM 0.0994 mL 0.4969 mL 0.9938 mL 2.4846 mL
40 mM 0.0745 mL 0.3727 mL 0.7454 mL 1.8634 mL
50 mM 0.0596 mL 0.2982 mL 0.5963 mL 1.4908 mL
60 mM 0.0497 mL 0.2485 mL 0.4969 mL 1.2423 mL
80 mM 0.0373 mL 0.1863 mL 0.3727 mL 0.9317 mL
100 mM 0.0298 mL 0.1491 mL 0.2982 mL 0.7454 mL
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17β-HSD1-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

17β-HSD1-IN-12760791-96-4Others17β-HSD1non-small cell lung cancerNSCLCInhibitorinhibitorinhibit

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