2',3',5'-Tri-O-acetyl-2-thiouridine

Cat. No.: HY-154170 Purity: 99.27%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

2',3',5'-Tri-O-acetyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

2',3',5'-Tri-O-acetyl-2-thiouridine Chemical Structure

CAS No. : 28542-31-6

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

386.38

Formula

C₁₅H₁₈N₂O₈S

CAS No.

28542-31-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(C=C1)NC(N1[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O)=S

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (647.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5881 mL	12.9406 mL	25.8813 mL
5 mM	0.5176 mL	2.5881 mL	5.1763 mL
10 mM	0.2588 mL	1.2941 mL	2.5881 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.27%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (256 KB) HNMR (260 KB) LCMS (98 KB)

Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5881 mL	12.9406 mL	25.8813 mL	64.7031 mL
	5 mM	0.5176 mL	2.5881 mL	5.1763 mL	12.9406 mL
	10 mM	0.2588 mL	1.2941 mL	2.5881 mL	6.4703 mL
	15 mM	0.1725 mL	0.8627 mL	1.7254 mL	4.3135 mL
	20 mM	0.1294 mL	0.6470 mL	1.2941 mL	3.2352 mL
	25 mM	0.1035 mL	0.5176 mL	1.0353 mL	2.5881 mL
	30 mM	0.0863 mL	0.4314 mL	0.8627 mL	2.1568 mL
	40 mM	0.0647 mL	0.3235 mL	0.6470 mL	1.6176 mL
	50 mM	0.0518 mL	0.2588 mL	0.5176 mL	1.2941 mL
	60 mM	0.0431 mL	0.2157 mL	0.4314 mL	1.0784 mL
	80 mM	0.0324 mL	0.1618 mL	0.3235 mL	0.8088 mL
	100 mM	0.0259 mL	0.1294 mL	0.2588 mL	0.6470 mL