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  3. 2,3-Di(furan-2-yl)quinoxaline

2,3-Di(furan-2-yl)quinoxaline (Compound 5) is a quinoxaline exhibiting blue fluorescence. 2,3-Di(furan-2-yl)quinoxaline is cell permeable and sufficiently bright at a micromolar concentration (1.5 μM).

For research use only. We do not sell to patients.

2,3-Di(furan-2-yl)quinoxaline Chemical Structure

2,3-Di(furan-2-yl)quinoxaline Chemical Structure

CAS No. : 57490-73-0

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
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10 mg USD 80 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

2,3-Di(furan-2-yl)quinoxaline (Compound 5) is a quinoxaline exhibiting blue fluorescence. 2,3-Di(furan-2-yl)quinoxaline is cell permeable and sufficiently bright at a micromolar concentration (1.5 μM)[1].

Molecular Weight

262.26

Formula

C16H10N2O2

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

C1(C2=CC=CO2)=NC3=CC=CC=C3N=C1C4=CC=CO4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (381.30 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8130 mL 19.0650 mL 38.1301 mL
5 mM 0.7626 mL 3.8130 mL 7.6260 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (9.53 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, PEG300/PEG400, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8130 mL 19.0650 mL 38.1301 mL 95.3252 mL
5 mM 0.7626 mL 3.8130 mL 7.6260 mL 19.0650 mL
10 mM 0.3813 mL 1.9065 mL 3.8130 mL 9.5325 mL
15 mM 0.2542 mL 1.2710 mL 2.5420 mL 6.3550 mL
20 mM 0.1907 mL 0.9533 mL 1.9065 mL 4.7663 mL
25 mM 0.1525 mL 0.7626 mL 1.5252 mL 3.8130 mL
30 mM 0.1271 mL 0.6355 mL 1.2710 mL 3.1775 mL
40 mM 0.0953 mL 0.4766 mL 0.9533 mL 2.3831 mL
50 mM 0.0763 mL 0.3813 mL 0.7626 mL 1.9065 mL
60 mM 0.0636 mL 0.3178 mL 0.6355 mL 1.5888 mL
80 mM 0.0477 mL 0.2383 mL 0.4766 mL 1.1916 mL
100 mM 0.0381 mL 0.1907 mL 0.3813 mL 0.9533 mL
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Product Name:
2,3-Di(furan-2-yl)quinoxaline
Cat. No.:
HY-153349
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