2-Fluoropalmitic acid

Name: 2-Fluoropalmitic acid
Brand: MedChemExpress
SKU: HY-117651
Rating: 4.5 (1 reviews)

Cat. No.: HY-117651 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invasion of glioma cell lines.

For research use only. We do not sell to patients.

2-Fluoropalmitic acid Chemical Structure

CAS No. : 16518-94-8

Size	Price	Stock	Quantity
5 mg	USD 240	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 385	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Acyltransferase Isoform Specific Products:

View All Isoforms

ACAT1 ACAT2 MGAT2 ACAT

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

274.41

Formula

C₁₆H₃₁FO₂

CAS No.

16518-94-8

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCCC(C(O)=O)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (364.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6442 mL	18.2209 mL	36.4418 mL
5 mM	0.7288 mL	3.6442 mL	7.2884 mL
10 mM	0.3644 mL	1.8221 mL	3.6442 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (9.11 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (265 KB) SDS (251 KB)

COA (239 KB) HNMR (254 KB) MS (79 KB)

Handling Instructions (2659 KB)

References

[1]. Shabierjiang Jiapaer 1, et al. Identification of 2-Fluoropalmitic Acid as a Potential Therapeutic Agent Against Glioblastoma. Curr Pharm Des. 2020;26(36):4675-4684. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.6442 mL	18.2209 mL	36.4418 mL	91.1046 mL
	5 mM	0.7288 mL	3.6442 mL	7.2884 mL	18.2209 mL
	10 mM	0.3644 mL	1.8221 mL	3.6442 mL	9.1105 mL
	15 mM	0.2429 mL	1.2147 mL	2.4295 mL	6.0736 mL
	20 mM	0.1822 mL	0.9110 mL	1.8221 mL	4.5552 mL
	25 mM	0.1458 mL	0.7288 mL	1.4577 mL	3.6442 mL
	30 mM	0.1215 mL	0.6074 mL	1.2147 mL	3.0368 mL
	40 mM	0.0911 mL	0.4555 mL	0.9110 mL	2.2776 mL
	50 mM	0.0729 mL	0.3644 mL	0.7288 mL	1.8221 mL
	60 mM	0.0607 mL	0.3037 mL	0.6074 mL	1.5184 mL
	80 mM	0.0456 mL	0.2278 mL	0.4555 mL	1.1388 mL
	100 mM	0.0364 mL	0.1822 mL	0.3644 mL	0.9110 mL