2-Hexylthiophene

Name: 2-Hexylthiophene
Brand: MedChemExpress
SKU: HY-34544
Rating: 4.5 (1 reviews)

Cat. No.: HY-34544 Purity: 97.41%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2-Hexylthiophene is an extremely weak basic heteroaromatic compound. 2-Hexylthiophene can be used to modify and improve the molar absorption coefficient of ruthenium sensitizer

For research use only. We do not sell to patients.

2-Hexylthiophene Chemical Structure

CAS No. : 18794-77-9

Size	Price	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 66	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 66	In-stock	Estimated Time of Arrival: December 31
Liquid
5 g	USD 60	Get quote	Estimated Time of Arrival: December 31
10 g	USD 105	Get quote	Estimated Time of Arrival: December 31
25 g	USD 200	Get quote	Estimated Time of Arrival: December 31
50 g		Get quote

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Biological Activity
Purity & Documentation
References
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Description

2-Hexylthiophene is an extremely weak basic heteroaromatic compound. 2-Hexylthiophene can be used to modify and improve the molar absorption coefficient of ruthenium sensitizer^[1]

In Vitro

2-Hexylthiophene is introduced to the 5-position of the terpyridine derivative ligand. And thereby, it helps to improve the molar absorption coefficient of ruthenium sensitizer.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

168.30

Formula

C₁₀H₁₆S

CAS No.

18794-77-9

Appearance

Liquid (Density: 0.946 g/cm³)

Color

Colorless to light yellow

SMILES

CCCCCCC1=CC=CS1

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (594.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.9418 mL	29.7089 mL	59.4177 mL
5 mM	1.1884 mL	5.9418 mL	11.8835 mL
10 mM	0.5942 mL	2.9709 mL	5.9418 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (14.85 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (14.85 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (14.85 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 98.89%

Select Batch:

Data Sheet (269 KB) SDS (393 KB)

COA (244 KB) HNMR (121 KB) GC (77 KB)

Handling Instructions (2659 KB)

References

[1]. Ozawa H, et al. Ruthenium sensitizers with a hexylthiophene-modified terpyridine ligand for dye-sensitized solar cells: synthesis, photo- and electrochemical properties, and adsorption behavior to the TiO2 surface.ACS Appl Mater Interfaces. 2015 Feb 11;7(5):3152-61. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.9418 mL	29.7089 mL	59.4177 mL	148.5443 mL
	5 mM	1.1884 mL	5.9418 mL	11.8835 mL	29.7089 mL
	10 mM	0.5942 mL	2.9709 mL	5.9418 mL	14.8544 mL
	15 mM	0.3961 mL	1.9806 mL	3.9612 mL	9.9030 mL
	20 mM	0.2971 mL	1.4854 mL	2.9709 mL	7.4272 mL
	25 mM	0.2377 mL	1.1884 mL	2.3767 mL	5.9418 mL
	30 mM	0.1981 mL	0.9903 mL	1.9806 mL	4.9515 mL
	40 mM	0.1485 mL	0.7427 mL	1.4854 mL	3.7136 mL
	50 mM	0.1188 mL	0.5942 mL	1.1884 mL	2.9709 mL
	60 mM	0.0990 mL	0.4951 mL	0.9903 mL	2.4757 mL
	80 mM	0.0743 mL	0.3714 mL	0.7427 mL	1.8568 mL
	100 mM	0.0594 mL	0.2971 mL	0.5942 mL	1.4854 mL