2-Hydroxy-4-methylbenzaldehyde

Name: 2-Hydroxy-4-methylbenzaldehyde
Brand: MedChemExpress
SKU: HY-W007888
Rating: 4.5 (1 reviews)

Cat. No.: HY-W007888 Purity: 99.94%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2-Hydroxy-4-methylbenzaldehyde is an endogenous metabolite.

For research use only. We do not sell to patients.

2-Hydroxy-4-methylbenzaldehyde Chemical Structure

CAS No. : 698-27-1

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Free Sample (0.1 - 0.5 mg)		Apply Now
1 g	USD 25	In-stock	Estimated Time of Arrival: December 31
5 g	USD 40	In-stock	Estimated Time of Arrival: December 31
10 g	USD 60	In-stock	Estimated Time of Arrival: December 31
50 g		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
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Description

2-Hydroxy-4-methylbenzaldehyde is an endogenous metabolite.

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

136.15

Formula

C₈H₈O₂

CAS No.

698-27-1

Appearance

Solid

Color

White to off-white

SMILES

O=CC1=CC=C(C)C=C1O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL (244.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.3448 mL	36.7242 mL	73.4484 mL
5 mM	1.4690 mL	7.3448 mL	14.6897 mL
10 mM	0.7345 mL	3.6724 mL	7.3448 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (18.36 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (18.36 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (18.36 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.94%

Select Batch:

Data Sheet (245 KB) SDS (393 KB)

COA (250 KB) HNMR (110 KB) GC (204 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	7.3448 mL	36.7242 mL	73.4484 mL	183.6210 mL
	5 mM	1.4690 mL	7.3448 mL	14.6897 mL	36.7242 mL
	10 mM	0.7345 mL	3.6724 mL	7.3448 mL	18.3621 mL
	15 mM	0.4897 mL	2.4483 mL	4.8966 mL	12.2414 mL
	20 mM	0.3672 mL	1.8362 mL	3.6724 mL	9.1811 mL
	25 mM	0.2938 mL	1.4690 mL	2.9379 mL	7.3448 mL
	30 mM	0.2448 mL	1.2241 mL	2.4483 mL	6.1207 mL
	40 mM	0.1836 mL	0.9181 mL	1.8362 mL	4.5905 mL
	50 mM	0.1469 mL	0.7345 mL	1.4690 mL	3.6724 mL
	60 mM	0.1224 mL	0.6121 mL	1.2241 mL	3.0604 mL
	80 mM	0.0918 mL	0.4591 mL	0.9181 mL	2.2953 mL
	100 mM	0.0734 mL	0.3672 mL	0.7345 mL	1.8362 mL