2. Cell Cycle/DNA Damage Epigenetics Apoptosis
  3. Sirtuin Apoptosis
  4. 4'-Bromo-resveratrol

4'-Bromo-resveratrol  (Synonyms: 4′‐BR)

Cat. No.: HY-124113 Purity: 99.79%
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4'-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3. 4'-Bromo-resveratrol inhibits melanoma cell growth through mitochondrial metabolic reprogramming. 4'-Bromo-resveratrol imparts antiproliferative effects in melanoma cells through a metabolic reprogramming and affecting the cell cycle and apoptosis signaling.

For research use only. We do not sell to patients.

4'-Bromo-resveratrol Chemical Structure

4'-Bromo-resveratrol Chemical Structure

CAS No. : 1224713-90-9

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
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10 mM * 1 mL in DMSO USD 94 In-stock
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Based on 1 publication(s) in Google Scholar

4'-Bromo-resveratrol Related Antibodies

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Description

4'-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3. 4'-Bromo-resveratrol inhibits melanoma cell growth through mitochondrial metabolic reprogramming. 4'-Bromo-resveratrol imparts antiproliferative effects in melanoma cells through a metabolic reprogramming and affecting the cell cycle and apoptosis signaling[1].

Molecular Weight

291.14

Formula

C14H11BrO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC(O)=CC(/C=C/C2=CC=C(C=C2)Br)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (858.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4348 mL 17.1739 mL 34.3477 mL
5 mM 0.6870 mL 3.4348 mL 6.8695 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4348 mL 17.1739 mL 34.3477 mL 85.8693 mL
5 mM 0.6870 mL 3.4348 mL 6.8695 mL 17.1739 mL
10 mM 0.3435 mL 1.7174 mL 3.4348 mL 8.5869 mL
15 mM 0.2290 mL 1.1449 mL 2.2898 mL 5.7246 mL
20 mM 0.1717 mL 0.8587 mL 1.7174 mL 4.2935 mL
25 mM 0.1374 mL 0.6870 mL 1.3739 mL 3.4348 mL
30 mM 0.1145 mL 0.5725 mL 1.1449 mL 2.8623 mL
40 mM 0.0859 mL 0.4293 mL 0.8587 mL 2.1467 mL
50 mM 0.0687 mL 0.3435 mL 0.6870 mL 1.7174 mL
60 mM 0.0572 mL 0.2862 mL 0.5725 mL 1.4312 mL
80 mM 0.0429 mL 0.2147 mL 0.4293 mL 1.0734 mL
100 mM 0.0343 mL 0.1717 mL 0.3435 mL 0.8587 mL
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4'-Bromo-resveratrol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4'-Bromo-resveratrol1224713-90-94′‐BRSirtuinApoptosisSirtuin-1Sirtuin-3melanoma cell growthmitochondrial metabolic reprogrammingantiproliferativecell cycleapoptosisInhibitorinhibitorinhibit

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