4'-Hydroxytamoxifen TFA

Cat. No.: HY-124414A: FAQs
Data Sheet Handling Instructions

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4'-Hydroxytamoxifen TFA is a salt form of a metabolite of Tamoxifen. 4'-Hydroxytamoxifen TFA has a higher affinity for ER than Tamoxifen. 4'-Hydroxytamoxifen TFA induces non-apoptotic cytotoxicity in human endometrial adenocarcinoma cells.

For research use only. We do not sell to patients.

4'-Hydroxytamoxifen TFA Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 290	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 465	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 930	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 1488	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 2380	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of 4'-Hydroxytamoxifen TFA:

4'-Hydroxytamoxifen Get quote

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•Related Small Molecules:

•Related Proteins:

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

501.54

Formula

C₂₈H₃₀F₃NO₄

SMILES

CC/C(C1=CC=C(C=C1)O)=C(C2=CC=C(C=C2)OCCN(C)C)\C3=CC=CC=C3.OC(C(F)(F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 35 mg/mL (69.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9939 mL	9.9693 mL	19.9386 mL
5 mM	0.3988 mL	1.9939 mL	3.9877 mL
10 mM	0.1994 mL	0.9969 mL	1.9939 mL

View the Complete Stock Solution Preparation Table

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Cuevas M E, et al. In vitro cytotoxicity of 4'-OH-tamoxifen and estradiol in human endometrial adenocarcinoma cells HEC-1A and HEC-1B[J]. Oncology Reports, 2015, 33(1): 464-470. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.9939 mL	9.9693 mL	19.9386 mL	49.8465 mL
	5 mM	0.3988 mL	1.9939 mL	3.9877 mL	9.9693 mL
	10 mM	0.1994 mL	0.9969 mL	1.9939 mL	4.9846 mL
	15 mM	0.1329 mL	0.6646 mL	1.3292 mL	3.3231 mL
	20 mM	0.0997 mL	0.4985 mL	0.9969 mL	2.4923 mL
	25 mM	0.0798 mL	0.3988 mL	0.7975 mL	1.9939 mL
	30 mM	0.0665 mL	0.3323 mL	0.6646 mL	1.6615 mL
	40 mM	0.0498 mL	0.2492 mL	0.4985 mL	1.2462 mL
	50 mM	0.0399 mL	0.1994 mL	0.3988 mL	0.9969 mL
	60 mM	0.0332 mL	0.1662 mL	0.3323 mL	0.8308 mL