5'-O-DMT-ibu-rG (Synonyms: 5'-O-DMT-N2-isobutyrylguanosine)

Cat. No.: HY-43058 Purity: 95.39%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

5'-O-DMT-ibu-rG is a useful model for a new class of DNA binding molecules for the development of potent and selective anti-cancer agents.

For research use only. We do not sell to patients.

5'-O-DMT-ibu-rG Chemical Structure

CAS No. : 81246-83-5

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Free Sample (0.1 - 0.5 mg)		Apply Now
1 g	USD 50	In-stock	Estimated Time of Arrival: December 31
5 g	USD 120	In-stock	Estimated Time of Arrival: December 31
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Description

5'-O-DMT-ibu-rG is a useful model for a new class of DNA binding molecules for the development of potent and selective anti-cancer agents^[1].

Molecular Weight

655.70

Formula

C₃₅H₃₇N₅O₈

CAS No.

81246-83-5

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(NC(C(C)C)=O)NC3=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 175 mg/mL (266.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5251 mL	7.6254 mL	15.2509 mL
5 mM	0.3050 mL	1.5251 mL	3.0502 mL
10 mM	0.1525 mL	0.7625 mL	1.5251 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.39%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (255 KB) HNMR (290 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Pradeepkumar Patel, et al. Synthesis, DNA binding and anti-leukemic activity of an aminoacyl nucleolipid. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5086-90. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5251 mL	7.6254 mL	15.2509 mL	38.1272 mL
	5 mM	0.3050 mL	1.5251 mL	3.0502 mL	7.6254 mL
	10 mM	0.1525 mL	0.7625 mL	1.5251 mL	3.8127 mL
	15 mM	0.1017 mL	0.5084 mL	1.0167 mL	2.5418 mL
	20 mM	0.0763 mL	0.3813 mL	0.7625 mL	1.9064 mL
	25 mM	0.0610 mL	0.3050 mL	0.6100 mL	1.5251 mL
	30 mM	0.0508 mL	0.2542 mL	0.5084 mL	1.2709 mL
	40 mM	0.0381 mL	0.1906 mL	0.3813 mL	0.9532 mL
	50 mM	0.0305 mL	0.1525 mL	0.3050 mL	0.7625 mL
	60 mM	0.0254 mL	0.1271 mL	0.2542 mL	0.6355 mL
	80 mM	0.0191 mL	0.0953 mL	0.1906 mL	0.4766 mL
	100 mM	0.0153 mL	0.0763 mL	0.1525 mL	0.3813 mL

5'-O-DMT-ibu-rG Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5'-O-DMT-ibu-rG81246-83-55'-O-DMT-N2-isobutyrylguanosineNucleoside Antimetabolite/AnalogInhibitorinhibitorinhibit

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