2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 5'-O-DMT-ibu-rG

5'-O-DMT-ibu-rG  (Synonyms: 5'-O-DMT-N2-isobutyrylguanosine)

Cat. No.: HY-43058 Purity: 95.39%
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5'-O-DMT-ibu-rG is a useful model for a new class of DNA binding molecules for the development of potent and selective anti-cancer agents.

For research use only. We do not sell to patients.

5'-O-DMT-ibu-rG Chemical Structure

5'-O-DMT-ibu-rG Chemical Structure

CAS No. : 81246-83-5

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5'-O-DMT-ibu-rG Related Antibodies

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Description

5'-O-DMT-ibu-rG is a useful model for a new class of DNA binding molecules for the development of potent and selective anti-cancer agents[1].

Molecular Weight

655.70

Formula

C35H37N5O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(NC(C(C)C)=O)NC3=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 175 mg/mL (266.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5251 mL 7.6254 mL 15.2509 mL
5 mM 0.3050 mL 1.5251 mL 3.0502 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5251 mL 7.6254 mL 15.2509 mL 38.1272 mL
5 mM 0.3050 mL 1.5251 mL 3.0502 mL 7.6254 mL
10 mM 0.1525 mL 0.7625 mL 1.5251 mL 3.8127 mL
15 mM 0.1017 mL 0.5084 mL 1.0167 mL 2.5418 mL
20 mM 0.0763 mL 0.3813 mL 0.7625 mL 1.9064 mL
25 mM 0.0610 mL 0.3050 mL 0.6100 mL 1.5251 mL
30 mM 0.0508 mL 0.2542 mL 0.5084 mL 1.2709 mL
40 mM 0.0381 mL 0.1906 mL 0.3813 mL 0.9532 mL
50 mM 0.0305 mL 0.1525 mL 0.3050 mL 0.7625 mL
60 mM 0.0254 mL 0.1271 mL 0.2542 mL 0.6355 mL
80 mM 0.0191 mL 0.0953 mL 0.1906 mL 0.4766 mL
100 mM 0.0153 mL 0.0763 mL 0.1525 mL 0.3813 mL
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5'-O-DMT-ibu-rG Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5'-O-DMT-ibu-rG81246-83-55'-O-DMT-N2-isobutyrylguanosineNucleoside Antimetabolite/AnalogInhibitorinhibitorinhibit

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