2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis Nucleoside Antimetabolite/Analog
  4. 5'-O-TBDMS-dU

5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides.

For research use only. We do not sell to patients.

5'-O-TBDMS-dU Chemical Structure

5'-O-TBDMS-dU Chemical Structure

CAS No. : 76223-04-6

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Based on 1 publication(s) in Google Scholar

5'-O-TBDMS-dU Related Antibodies

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Description

5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides[1].

Molecular Weight

342.46

Formula

C15H26N2O5Si
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H](C[C@H](N1C(NC(C=C1)=O)=O)O2)[C@H]2CO[Si](C)(C)C(C)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (292.00 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9200 mL 14.6002 mL 29.2005 mL
5 mM 0.5840 mL 2.9200 mL 5.8401 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9200 mL 14.6002 mL 29.2005 mL 73.0012 mL
5 mM 0.5840 mL 2.9200 mL 5.8401 mL 14.6002 mL
10 mM 0.2920 mL 1.4600 mL 2.9200 mL 7.3001 mL
15 mM 0.1947 mL 0.9733 mL 1.9467 mL 4.8667 mL
20 mM 0.1460 mL 0.7300 mL 1.4600 mL 3.6501 mL
25 mM 0.1168 mL 0.5840 mL 1.1680 mL 2.9200 mL
30 mM 0.0973 mL 0.4867 mL 0.9733 mL 2.4334 mL
40 mM 0.0730 mL 0.3650 mL 0.7300 mL 1.8250 mL
50 mM 0.0584 mL 0.2920 mL 0.5840 mL 1.4600 mL
60 mM 0.0487 mL 0.2433 mL 0.4867 mL 1.2167 mL
80 mM 0.0365 mL 0.1825 mL 0.3650 mL 0.9125 mL
100 mM 0.0292 mL 0.1460 mL 0.2920 mL 0.7300 mL
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5'-O-TBDMS-dU Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5'-O-TBDMS-dU76223-04-6DNA/RNA SynthesisNucleoside Antimetabolite/AnalogInhibitorinhibitorinhibit

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