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Enecadin is a neuroprotective agent extracted from patent US 8623823 B2.

For research use only. We do not sell to patients.

Enecadin Chemical Structure

Enecadin Chemical Structure

CAS No. : 259525-01-4

Size Price Stock Quantity
1 mg USD 340 In-stock
5 mg USD 850 In-stock
10 mg USD 1150 In-stock
25 mg USD 1650 In-stock
50 mg USD 2200 In-stock
100 mg USD 3100 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Enecadin:

Enecadin Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Enecadin is a neuroprotective agent extracted from patent US 8623823 B2.

In Vitro

Enecadin is a neuroprotective agent which can be useful for the treatment of stroke or other cerebrovascular accident[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Enecadin Related Antibodies
Clinical Trial
Molecular Weight

357.46

Formula

C21H28FN3O
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC1=NC(OCCCCCN2CCCCC2)=CC(C3=CC=C(F)C=C3)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (139.88 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7975 mL 13.9876 mL 27.9752 mL
5 mM 0.5595 mL 2.7975 mL 5.5950 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.08 mg/mL (5.82 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.08 mg/mL (5.82 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7975 mL 13.9876 mL 27.9752 mL 69.9379 mL
5 mM 0.5595 mL 2.7975 mL 5.5950 mL 13.9876 mL
10 mM 0.2798 mL 1.3988 mL 2.7975 mL 6.9938 mL
15 mM 0.1865 mL 0.9325 mL 1.8650 mL 4.6625 mL
20 mM 0.1399 mL 0.6994 mL 1.3988 mL 3.4969 mL
25 mM 0.1119 mL 0.5595 mL 1.1190 mL 2.7975 mL
30 mM 0.0933 mL 0.4663 mL 0.9325 mL 2.3313 mL
40 mM 0.0699 mL 0.3497 mL 0.6994 mL 1.7484 mL
50 mM 0.0560 mL 0.2798 mL 0.5595 mL 1.3988 mL
60 mM 0.0466 mL 0.2331 mL 0.4663 mL 1.1656 mL
80 mM 0.0350 mL 0.1748 mL 0.3497 mL 0.8742 mL
100 mM 0.0280 mL 0.1399 mL 0.2798 mL 0.6994 mL
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Enecadin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Enecadin259525-01-4OthersInhibitorinhibitorinhibit

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