2. Natural Products
  3. Plants Phenylpropanoids
  4. Meliaceae Lignans
  5. Toona sinensis (A. Juss.) Roem.
  6. Lyoniresinol

Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM.

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Lyoniresinol Chemical Structure

Lyoniresinol Chemical Structure

CAS No. : 14464-90-5

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Based on 1 publication(s) in Google Scholar

Other Forms of Lyoniresinol:

Lyoniresinol Related Antibodies

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Description

Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM[1].

IC50 & Target

IC50: 82.4 μM (DPPH)[1]
Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 30 μM
Compound: 15
Anticancer activity against human A549 cells by SRB assay
Anticancer activity against human A549 cells by SRB assay
[PMID: 21420296]
SK-MEL-2 IC50
> 30 μM
Compound: 15
Anticancer activity against human SK-MEL-2 cells by SRB assay
Anticancer activity against human SK-MEL-2 cells by SRB assay
[PMID: 21420296]
SK-OV-3 IC50
> 30 μM
Compound: 15
Anticancer activity against human SKOV3 cells by SRB assay
Anticancer activity against human SKOV3 cells by SRB assay
[PMID: 21420296]
XF498 IC50
7.14 μM
Compound: 15
Anticancer activity against human XF498 cells by SRB assay
Anticancer activity against human XF498 cells by SRB assay
[PMID: 21420296]
In Vitro

Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lyoniresinol Related Antibodies
Molecular Weight

420.45

Formula

C22H28O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](C2=CC(OC)=C(O)C(OC)=C2)C3=C(OC)C(O)=C(OC)C=C3C[C@H]1CO
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 4.5 mg/mL (10.70 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3784 mL 11.8920 mL 23.7840 mL
5 mM 0.4757 mL 2.3784 mL 4.7568 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3784 mL 11.8920 mL 23.7840 mL 59.4601 mL
5 mM 0.4757 mL 2.3784 mL 4.7568 mL 11.8920 mL
10 mM 0.2378 mL 1.1892 mL 2.3784 mL 5.9460 mL
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Lyoniresinol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lyoniresinol14464-90-5OthersligninTarenna attenuateantioxidantDPPHInhibitorinhibitorinhibit

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