2. Natural Products
  3. Plants
  4. Polygalaceae
  5. Polygala tenuifolia Willd.

Polygala tenuifolia Willd.

Polygala tenuifolia Willd. (47):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W012123
    3,4,5-Trimethoxycinnamic acid 90-50-6 99.79%
    3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of Polygala tenuifolia WILLD, with anti-stress effect, prolonging the sleeping time in animals. 3,4,5-Trimethoxycinnamic acid increases expression of GAD65 and γ-subunit of GABAA receptor, but shows no effect on the amounts of α-, β-subunits.
    3,4,5-Trimethoxycinnamic acid
  • HY-N0802
    Tenuigenin 2469-34-3 99.24%
    Tenuigenin is a major active component isolated from the root of the Chinese herb Polygala tenuifolia. Tenuigenin protects against S.aureus-induced pneumonia by inhibiting NF-κB activation. Tenuigenin has anti-inflammatory effect.
    Tenuigenin
  • HY-N0702
    Tenuifolin 20183-47-5 99.24%
    Tenuifolin is effective and has a protective action. Tenuifolin inhibits β-secretase decreases Aβ protein secretion, suppresses Aβ25-35 secretion, and subsequently caspase-3 and caspase-9 become active. Tenuifolin's ability to lower AChE activity, increase at the same time, increase the ability of the upper glands, and improve the ability to read and remember. Research on tenuifolin's potential for use in urinary disease (AD).
    Tenuifolin
  • HY-N2167
    Sibiricose A5 107912-97-0 98.67%
    Sibiricose A5 is an oligosaccharide ester isolated from Polygalae Radix with potent antioxidant activity.
    Sibiricose A5
  • HY-N6076
    Tenuifoliside A 139726-35-5 98.07%
    Tenuifoliside A is isolated from Polygala tenuifolia, has anti-apoptotic and antidepressant-like effects. Tenuifoliside A exhibits its neneurotrophic effects and promotes cell proliferation through the ERK/CREB/BDNF signal pathway in C6 cells.
    Tenuifoliside A
  • HY-N2099
    Onjisaponin B 35906-36-6 99.10%
    Onjisaponin B is an orally active natural product derived from Polygala tenuifolia. Onjisaponin B inhibits NF-κB p65. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin. Onjisaponin B reduces β-amyloid (Aβ) production. Onjisaponin B reduces radiation-induced cell apoptosis. Onjisaponin B has anti-oxidant and anti-inflammatory activities. Onjisaponin B can be used for neurological disease and radiation injury study, and its metabolite tenuifolin (TF) can enter the brain through the BBB.
    Onjisaponin B
  • HY-N4279
    Gentisin 437-50-3 98.88%
    Gentisin is a natural compound isolated from Gentianae radix (Gentianaceae) with mutagenic activities.
    Gentisin
  • HY-N2498
    Glomeratose A 202471-84-9 99.89%
    Glomeratose A is a lactate dehydrogenase inhibitor, isolated from Polygala tenuifolia.
    Glomeratose A
  • HY-N1407
    Polygalaxanthone III 162857-78-5 99.76%
    Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM.
    Polygalaxanthone III
  • HY-N1414
    (E)-3',6-Disinapoylsucrose 139891-98-8 99.59%
    (E)-3',6-Disinapoylsucrose, the index component of Yuanzhi (Polygala tenuifolia Willd), possesses potent antioxidant activity and antidepressant effect.
    (E)-3',6-Disinapoylsucrose
  • HY-N2216
    Polygalasaponin XXXI 79103-90-5
    Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection.
    Polygalasaponin XXXI
  • HY-N2586
    Tenuifoliside C 139726-37-7 99.57%
    Tenuifoliside C, isolated from polygala tenuifolia willd, significantly inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.
    Tenuifoliside C
  • HY-N4268
    Tenuifoliside B 139726-36-6 99.21%
    Tenuifoliside B, a component isolated from Polygalae Radix, inhibits potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment. Tenuifoliside B shows potential cognitive improvement and cerebral protective effects. Tenuifoliside B has potential to become an anti-AD lead compound.
    Tenuifoliside B
  • HY-N0801
    Polygalacic acid 22338-71-2 98.92%
    Polygalacic acid, is a triterpene, isolated from the root of Polygala tenuifolia Willd. Polygalacic acid inhibits MMP expression. Polygalacic acid may have a therapeutic effect in Osteoarthritis (OA) treatment . Polygalacic acid exerts a significant neuroprotective effect on cognitive impairment, PA improves cholinergic system reactivity by inhibiting acetylcholinesterase (AChE) activity, increasing choline acetyltransferase (ChAT) activity, and elevating levels of acetylcholine (Ach) in the hippocampus and frontal cortex.
    Polygalacic acid
  • HY-N2171
    Sibiricaxanthone B 241125-81-5 99.12%
    Sibiricaxanthone B is a xanthone isolated from Polygala tenuifolia.
    Sibiricaxanthone B
  • HY-N4325
    Onjisaponin Z 1078708-72-1
    Onjisaponin Z is a natural product isolated from Radix Polygalae.
    Onjisaponin Z
  • HY-N6803
    Polygalaxanthone XI 857859-82-6 ≥99.0%
    Polygalaxanthone XI, a xanthone glycoside isolated from the cortexes of Polygala tenuifolia, can be used in the study of expectorant, and tranquilizing agent.
    Polygalaxanthone XI
  • HY-N2159
    Lancerin 81991-99-3 99.69%
    Lancerin, isolated from the root bark of Cudraniu cochinchinensis, possesses anti-lipid peroxidation.
    Lancerin
  • HY-N1479
    Polygalic acid 1260-04-4 99.25%
    Polygalic acid, a triterpenoid saponin, is considered one of the major active constituents of Polygala tenuifolia.
    Polygalic acid
  • HY-N12433
    Tenuiphenone B 870298-00-3
    Tenuiphenone B is a benzophenone isolated from the ethanolic extract of Polygala tenuifolia.
    Tenuiphenone B