Dopamine Receptor

Dopamine Receptor Related Products (490):

By Type:	Pan (5) Selective (1)
By Effects:	Controls (5) Inhibitors (89) Agonists (104) Antagonists (191) Activators (11) Modulators (18) Chemical (1)

Cat. No.	Product Name	Effect	Purity

HY-B1110

Nomifensine	Inhibitor	98.93%
Nomifensine ((±)-Nomifensine) is a potent norepinephrine (NE) and dopamine (DA) reuptake inhibitor. Nomifensine inhibits uptake of NE, DA and 5-HT in rat brain synaptosomes, with IC₅₀ values of 6.6 nM, 48 nM and 830 nM, and K_i values of 4.7 nM, 26 nM and 4000 nM, respectively. Nomifensine shows low or ineffective binding activity to dopamine D2, α1-adrenergic, 5-HT2, and muscarinic receptors. Nomifensine has antidepressive effects.

HY-128770

LY3154207	Agonist	99.87%
LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC₅₀=3 nM).

HY-109157

Ralmitaront		99.92%
Ralmitaront (RO6889450) is an orally active agonist of trace amine-associated receptor 1 (TAAR1) with a EC₅₀ value of 110.4 nM. Ralmitaront has antipsychotic, cognitively improvement, and antidepressant activity in rodents. Ralmitaront can be used as a neurosuppressant in the study of neuro-related diseases, such as schizophrenia (SCZ), schizoaffective disorder.

HY-137262

Protein deglycase DJ-1 against-1	Inhibitor	99.86%
Protein deglycase DJ-1 against-1, a DJ-1-binding compound, dependently targets DJ1. Protein deglycase DJ-1 against-1 penetrates through the blood brain barrier (BBB). Protein deglycase DJ-1 against-1 is used as a neuroprotective agent and has the potential for Parkinson's disease research.

HY-119486

Tavapadon	Agonist	99.94%
Tavapadon (PF-06649751) is an orally active and highly selective dopamine D1/D5 receptor partial agonist. Tavapadon is effective in enabling movement and reducing disability and has the potential for Parkinson's disease.

HY-B1110A

Nomifensine maleate	Inhibitor	98.79%
Nomifensine ((±)-Nomifensine) maleate is a potent norepinephrine (NE) and dopamine (DA) reuptake inhibitor. Nomifensine maleate inhibits uptake of NE, DA and 5-HT in rat brain synaptosomes, with IC₅₀ values of 6.6 nM, 48 nM and 830 nM, and K_i values of 4.7 nM, 26 nM and 4000 nM, respectively. Nomifensine maleate shows low or ineffective binding activity to dopamine D2, α1-adrenergic, 5-HT2, and muscarinic receptors. Nomifensine maleate has antidepressive effects.

HY-B1613A

Clebopride malate	Antagonist	99.72%
Clebopride malate is a dopamine antagonist used in the study of functional gastrointestinal disorders.

HY-13736A

Quinagolide hydrochloride	Agonist	99.69%
Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist. Quinagolide hydrochloride is an inhibitor of prolactin. Quinagolide hydrochloride down-regulates AKT levels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used for the research of cancer.

HY-B1059

Levosulpiride	Antagonist	99.88%
Levosulpiride (RV-12309) is the (S)-enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic agent of the benzamide class.

HY-B1470

Azaperone	Antagonist	99.68%
Azaperone (R-1929) acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.

HY-123538

GRK2 Inhibitor 1	Modulator	98.06%
GRK2 Inhibitor 1 (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a GRK2 (β-ARK1) inhibitor.

HY-108510

Rimcazole dihydrochloride	Inhibitor	99.96%
Rimcazole (BW 234U) dihydrochloride is a carbazole derivative that acts in part as a sigma (σ) receptor antagonist. Rimcazole dihydrochloride also binds with moderate affinity to the dopamine transporter and inhibit dopamine uptake. Rimcazole dihydrochloride can reduce locomotor activity and sensitization. Rimcazole dihydrochloride also can be used for the research of cancer.

HY-B0451AS4

Dopamine-d₃ hydrochloride		99.30%
Dopamine-d₃ (hydrochloride) is the deuterium labeled Dopamine hydrochloride (ASL279)-[1].

HY-W069508

3-(Aminomethyl)phenol	Inhibitor	99.34%
3-(Aminomethyl)phenol (m-Hydroxybenzylamine) reduces prefrontal Dopemine (DA) levels.

HY-119677

Oxypertine	Agonist	99.84%
Oxypertine is a neuroprotective agent. Oxypertine can be used in the research of neurological conditions, such as anxiety and schizophrenia.

HY-113468AS

3-O-Methyldopa-d₃	Inhibitor	99.34%
3-O-Methyldopa-d₃ (3-Methoxy-L-tyrosine-d₃) is deuterium labeled 3-O-Methyldopa (HY-113468A). 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine.

HY-107969

Haloperidol decanoate	Antagonist	99.67%
Haloperidol decanoate shows antipsychotic activity. Haloperidol decanoate can be used in schizophrenia and schizoaffective disorder research.

HY-P1764

Secretoneurin, rat	Activator	99.59%
Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII). Secretoneurin, rat induces dopamine release in the rat striatum in vivo and in vitro, and it exerts a very strong chemotactic effect on monocytes and eosinophils but not on granulocytes.

HY-12751A

Trimethobenzamide hydrochloride	Inhibitor	99.92%
Trimethobenzamide hydrochloride is a blocker of the D₂ receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.

HY-103417

SKF 77434 hydrobromide	Agonist	99.2%
SKF 77434 hydrobromide is a selective dopamine D1 receptor partial agonist. SKF 77434 hydrobromide has the potential to study cocaine addiction.

Name
Email *

	Sorry, but the email address you supplied was invalid.