Haloperidol decanoate

Name: Haloperidol decanoate
Brand: MedChemExpress
SKU: HY-107969
Rating: 4.5 (1 reviews)

Cat. No.: HY-107969 Purity: 99.67%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Haloperidol decanoate shows antipsychotic activity. Haloperidol decanoate can be used in schizophrenia and schizoaffective disorder research.

For research use only. We do not sell to patients.

Haloperidol decanoate Chemical Structure

CAS No. : 74050-97-8

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 61	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 61	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 52	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 88	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 178	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 265	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 391	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

or Bulk Inquiry

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Haloperidol decanoate:

Haloperidol decanoate (Standard) Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Haloperidol decanoate shows antipsychotic activity. Haloperidol decanoate can be used in schizophrenia and schizoaffective disorder research^[1].

Clinical Trial

Molecular Weight

530.11

Formula

C₃₁H₄₁ClFNO₃

CAS No.

74050-97-8

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCC(OC1(C2=CC=C(Cl)C=C2)CCN(CCCC(C3=CC=C(F)C=C3)=O)CC1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (188.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8864 mL	9.4320 mL	18.8640 mL
5 mM	0.3773 mL	1.8864 mL	3.7728 mL
10 mM	0.1886 mL	0.9432 mL	1.8864 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (4.72 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.67%

Select Batch:

Data Sheet (269 KB) SDS (392 KB)

COA (249 KB) HNMR (270 KB) LCMS (98 KB)

Handling Instructions (2659 KB)

References

[1]. R Beresford, et al. Haloperidol decanoate. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in psychosis. Drugs. 1987 Jan;33(1):31-49. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.8864 mL	9.4320 mL	18.8640 mL	47.1600 mL
	5 mM	0.3773 mL	1.8864 mL	3.7728 mL	9.4320 mL
	10 mM	0.1886 mL	0.9432 mL	1.8864 mL	4.7160 mL
	15 mM	0.1258 mL	0.6288 mL	1.2576 mL	3.1440 mL
	20 mM	0.0943 mL	0.4716 mL	0.9432 mL	2.3580 mL
	25 mM	0.0755 mL	0.3773 mL	0.7546 mL	1.8864 mL
	30 mM	0.0629 mL	0.3144 mL	0.6288 mL	1.5720 mL
	40 mM	0.0472 mL	0.2358 mL	0.4716 mL	1.1790 mL
	50 mM	0.0377 mL	0.1886 mL	0.3773 mL	0.9432 mL
	60 mM	0.0314 mL	0.1572 mL	0.3144 mL	0.7860 mL
	80 mM	0.0236 mL	0.1179 mL	0.2358 mL	0.5895 mL
	100 mM	0.0189 mL	0.0943 mL	0.1886 mL	0.4716 mL