Drug Isomer Control

Drug Isomer Controls (20):

Cat. No.	Product Name	Effect	Purity

HY-N0521

(-)-Gallocatechin	Control	99.96%
(-)-Gallocatechin, an epimer of (-)-Epigallocatechin (EGC), is contained in various tea products. (-)-Gallocatechin has antioxidant activities.

HY-76542B

(R)-Vitamin D2	Control	98.67%
(R)-Vitamin D2 is the isomer of Vitamin D2 (HY-76542), and can be used as an experimental control. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D.

HY-110258B

(R,S,R)-ML334	Control	98.57%
(R,S,R)-ML334 is the isomer of ML334 (HY-110258), and can be used as an experimental control. ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a K_d of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity.

HY-124883

R-(–)-Flecainide	Control	99.90%
R-(–)-Flecainide is an orally active antiarrhythmic agent, which inhibits ventricular ectopic activity.

HY-100540C

Golgicide A-1	Control	99.94%
Golgicide A-1 (GCA-1) is a less active cis-diastereomer of Golgicide A (GCA). Golgicide A-1 weakly inhibits mosquito reproduction.

HY-N7199

(Rac)-Hydnocarpin	Control
(Rac)-Hydnocarpin is a flavonoid isolated from Hydnocarpus anthelminthica, and exhibits moderate cytotoxic on cancer cells.

HY-145388B

AU-16235	Control	99.52%
AU-16235 is an inactive epimer of AU-15330. AU-16235 has no effect on cancer cell survival and growth

HY-107842

(Z)-JIB-04	Control	99.42%
(Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis.

HY-139534A

(S)-ARI-1	Control	99.80%
(S)-ARI-1 is an S-enantiomer of ARI-1. ARI-1 is a ROR1 inhibitor and apoptosis inducer, used in NSCLC research.

HY-145572B

(S)-Imlunestrant tosylate	Control	98.74%
(S)-Imlunestrant ((S)-LY-3484356) tosylate is an (S)-enantiomer of Imlunestrant (HY-145572). (S)-Imlunestrant tosylate can be used in research of cancer.

HY-126069

15(R)-Iloprost	Control
15(R)-Iloprost is the unnatural or inverted C-15 epimer of lloprost (HY-A0096).

HY-N6008A

7β-O-Methylmorroniside	Control
7β-O-Methylmorroniside (7R-O-methylmorroniside) is a R-isomer of 7-O-Methyl morroniside.

HY-15344A

(S,S)-Ketone monoester	Control
(S,S)-Ketone monoester is a (S,S)-enantiomer of Ketone monoester (HY-15344). Ketone monoester elevates the AcAc and acetone levels, thereby produces sustained ketosis and significantly delays central nervous system oxygen toxicity (CNS-OT) seizures.

HY-113887A

11β-Prostaglandin F1β	Control
11β-Prostaglandin F1β (11β-PGF1β) is a stereoisomer of PGF1α with inverted C-9 and C-11 hydroxyl groups.

HY-139553A

(R)-Zunsemetinib	Control
(R)-Zunsemetinib is the isomer of Zunsemetinib (HY-139553), and can be used as an experimental control. Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases.

HY-117799C

(±)-LY-426965 dihydrochloride	Control
(±)-LY-426965 dihydrochloride is a racemate of LY-426965 (HY-117799). LY426965 is a potent 5-HT1A receptor antagonist.

HY-W202854

Methiopropamine 3’-thiophene isomer hydrochloride	Control
Methiopropamine 3’-thiophene isomer is an isomer of Methiopropamine that has the sulfur atom of the thiophene group at the 3 position.

HY-113145

(Rac)-Salvianic acid A	Control
(Rac)-Salvianic acid A is the racemate of Salvianic acid A (HY-N1913). Salvianic acid A, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research.

HY-125922

(22R)-Budesonide	Control
(22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity.

HY-Z3151

3'-(2-Fluorophenyl) ezetimibe	Control
3'-(2-Fluorophenyl) ezetimibe is an isomer of the cholesterol transport inhibitor Ezetimibe (HY-17376).

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