2. Signaling Pathways
  3. Others
  4. Drug Isomer
  5. Drug Isomer Control

Drug Isomer Control

Drug Isomer Controls (23):

Cat. No. Product Name Effect Purity
  • HY-N0521
    (-)-Gallocatechin
    		Control 99.96%
    (-)-Gallocatechin, an epimer of (-)-Epigallocatechin (EGC), is contained in various tea products. (-)-Gallocatechin has antioxidant activities.
  • HY-100218C
    (1R,3R)-RSL3
    		Control 99.52%
    (1R,3R)-RSL3 is an isomer of RSL3 (HY-100218A). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells.
  • HY-76542B
    (R)-Vitamin D2
    		Control 98.67%
    (R)-Vitamin D2 is the isomer of Vitamin D2 (HY-76542), and can be used as an experimental control. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D.
  • HY-110258B
    (R,S,R)-ML334
    		Control 98.57%
    (R,S,R)-ML334 is the isomer of ML334 (HY-110258), and can be used as an experimental control. ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a Kd of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity.
  • HY-124883
    R-(–)-Flecainide
    		Control 99.90%
    R-(–)-Flecainide is an orally active antiarrhythmic agent, which inhibits ventricular ectopic activity.
  • HY-100540C
    Golgicide A-1
    		Control 99.94%
    Golgicide A-1 (GCA-1) is a less active cis-diastereomer of Golgicide A (GCA). Golgicide A-1 weakly inhibits mosquito reproduction.
  • HY-N7199
    (Rac)-Hydnocarpin
    		Control
    (Rac)-Hydnocarpin is a flavonoid isolated from Hydnocarpus anthelminthica, and exhibits moderate cytotoxic on cancer cells.
  • HY-145388B
    AU-16235
    		Control 99.52%
    AU-16235 is an inactive epimer of AU-15330. AU-16235 has no effect on cancer cell survival and growth
  • HY-107842
    (Z)-JIB-04
    		Control 99.42%
    (Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis.
  • HY-139534A
    (S)-ARI-1
    		Control 99.80%
    (S)-ARI-1 is an S-enantiomer of ARI-1. ARI-1 is a ROR1 inhibitor and apoptosis inducer, used in NSCLC research.
  • HY-145572B
    (S)-Imlunestrant tosylate
    		Control 98.74%
    (S)-Imlunestrant ((S)-LY-3484356) tosylate is an (S)-enantiomer of Imlunestrant (HY-145572). (S)-Imlunestrant tosylate can be used in research of cancer.
  • HY-126069
    15(R)-Iloprost
    		Control
    15(R)-Iloprost is the unnatural or inverted C-15 epimer of lloprost (HY-A0096).
  • HY-N6008A
    7β-O-Methylmorroniside
    		Control
    7β-O-Methylmorroniside (7R-O-methylmorroniside) is a R-isomer of 7-O-Methyl morroniside.
  • HY-15954A
    NVP-CGM097 (stereoisomer)
    		Control
    NVP-CGM097 (stereoisomer) is a stereoisomer of NVP-CGM097, with no special bioactivity. NVP-CGM097 is a potent and selective MDM2 inhibitor.
  • HY-15344A
    (S,S)-Ketone monoester
    		Control
    (S,S)-Ketone monoester is a (S,S)-enantiomer of Ketone monoester (HY-15344). Ketone monoester elevates the AcAc and acetone levels, thereby produces sustained ketosis and significantly delays central nervous system oxygen toxicity (CNS-OT) seizures.
  • HY-113887A
    11β-Prostaglandin F1β
    		Control
    11β-Prostaglandin F1β (11β-PGF1β) is a stereoisomer of PGF1α with inverted C-9 and C-11 hydroxyl groups.
  • HY-139553A
    (R)-Zunsemetinib
    		Control
    (R)-Zunsemetinib is the isomer of Zunsemetinib (HY-139553), and can be used as an experimental control. Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases.
  • HY-117799C
    (±)-LY-426965 dihydrochloride
    		Control
    (±)-LY-426965 dihydrochloride is a racemate of LY-426965 (HY-117799). LY426965 is a potent 5-HT1A receptor antagonist.
  • HY-W202854
    Methiopropamine 3’-thiophene isomer hydrochloride
    		Control
    Methiopropamine 3’-thiophene isomer is an isomer of Methiopropamine that has the sulfur atom of the thiophene group at the 3 position.
  • HY-113145
    (Rac)-Salvianic acid A
    		Control
    (Rac)-Salvianic acid A is the racemate of Salvianic acid A (HY-N1913). Salvianic acid A, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research.