2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Adenosine 5'-diphosphate sodium salt

Adenosine 5'-diphosphate sodium salt 

Cat. No.: HY-W010791 Purity: ≥98.0%
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Adenosine 5'-diphosphate (ADP) sodium salt is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.

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Adenosine 5'-diphosphate sodium salt Chemical Structure

Adenosine 5'-diphosphate sodium salt Chemical Structure

CAS No. : 20398-34-9

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Based on 1 publication(s) in Google Scholar

Other Forms of Adenosine 5'-diphosphate sodium salt:

Adenosine 5'-diphosphate sodium salt Related Antibodies

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1 Publications Citing Use of MCE Adenosine 5'-diphosphate sodium salt

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Description

Adenosine 5'-diphosphate (ADP) sodium salt is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

Cellular Effect
Cell Line Type Value Description References
Cerebral cortex neuron EC50
19 μM
Compound: 2
Neuroprotective activity against Fe2+-induced oxidative damage in rat primary cortical neurons assessed as cell viability after 24 hrs by MTT assay
Neuroprotective activity against Fe2+-induced oxidative damage in rat primary cortical neurons assessed as cell viability after 24 hrs by MTT assay
[PMID: 26447940]
PC-12 IC50
21 μM
Compound: 2
Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced reactive oxygen species formation after 1 hr by DCFH-DA dye-based fluorometric analysis
Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced reactive oxygen species formation after 1 hr by DCFH-DA dye-based fluorometric analysis
[PMID: 26447940]
PC-12 IC50
21 μM
Compound: 2, ADP
Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced ROS production after 1 hr by DCFH-DA staining-based fluorometric analysis
Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced ROS production after 1 hr by DCFH-DA staining-based fluorometric analysis
[PMID: 23751098]
Clinical Trial
Formula

C10H15N5O10P2.xNa
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=C(N=CN2[C@@]3([H])[C@@](O)([H])[C@@](O)([H])[C@@](O3)([H])COP(O)(OP(O)(O)=O)=O)C2=NC=N1.[x].[Na]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation

Purity: ≥98.0%

SDS (393 KB)

COA (253 KB) HNMR (127 KB) LCMS (130 KB)

Handling Instructions (2659 KB)
References
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Adenosine 5'-diphosphate sodium salt Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adenosine 5'-diphosphate20398-34-9Endogenous MetaboliteInhibitorinhibitorinhibit

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