2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Adenosine 5'-diphosphate

Adenosine 5'-diphosphate  (Synonyms: Adenosine diphosphate; ADP)

Cat. No.: HY-W010918 Purity: 98.90%
COA Handling Instructions

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Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.

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Adenosine 5'-diphosphate Chemical Structure

Adenosine 5'-diphosphate Chemical Structure

CAS No. : 58-64-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
100 mg USD 50 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Adenosine 5'-diphosphate:

Adenosine 5'-diphosphate Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Adenosine 5'-diphosphate

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Adenosine 5'-diphosphate Related Antibodies
Clinical Trial
Molecular Weight

427.20

Formula

C10H15N5O10P2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(O)(OP(O)(OC[C@H]1O[C@@H](N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O)=O)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (117.04 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3408 mL 11.7041 mL 23.4082 mL
5 mM 0.4682 mL 2.3408 mL 4.6816 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (234.08 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.90%

COA (252 KB) HNMR (274 KB) RP-HPLC (259 KB) LCMS (93 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.3408 mL 11.7041 mL 23.4082 mL 58.5206 mL
5 mM 0.4682 mL 2.3408 mL 4.6816 mL 11.7041 mL
10 mM 0.2341 mL 1.1704 mL 2.3408 mL 5.8521 mL
15 mM 0.1561 mL 0.7803 mL 1.5605 mL 3.9014 mL
20 mM 0.1170 mL 0.5852 mL 1.1704 mL 2.9260 mL
25 mM 0.0936 mL 0.4682 mL 0.9363 mL 2.3408 mL
30 mM 0.0780 mL 0.3901 mL 0.7803 mL 1.9507 mL
40 mM 0.0585 mL 0.2926 mL 0.5852 mL 1.4630 mL
50 mM 0.0468 mL 0.2341 mL 0.4682 mL 1.1704 mL
60 mM 0.0390 mL 0.1951 mL 0.3901 mL 0.9753 mL
80 mM 0.0293 mL 0.1463 mL 0.2926 mL 0.7315 mL
100 mM 0.0234 mL 0.1170 mL 0.2341 mL 0.5852 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Adenosine 5'-diphosphate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adenosine 5'-diphosphate58-64-0Adenosine diphosphate ADPEndogenous MetaboliteInhibitorinhibitorinhibit

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